RFX4-AS1

Summary

RFX4-AS1 (RFX4 antisense RNA 1, HGNC:58967) is a long non-coding RNA gene on chromosome 12q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58967
Approved symbol	RFX4-AS1
Name	RFX4 antisense RNA 1
Location	12q23.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.346
Ensembl gene	ENSG00000257545
Ensembl biotype	lncRNA
Entrez	100287944

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000549203, ENST00000551505, ENST00000652234, ENST00000716378, ENST00000716379, ENST00000716380, ENST00000716381, ENST00000716382, ENST00000716383, ENST00000716384, ENST00000716385, ENST00000716386, ENST00000716387, ENST00000730862, ENST00000730863, ENST00000741234, ENST00000839327, ENST00000839328, ENST00000839329

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000549203 — 4 exons

Exon	Start	End
ENSE00002350855	106774690	106774831
ENSE00002362444	106496410	106496546
ENSE00002420497	106507628	106507810
ENSE00003760261	106500076	106500182

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 78.52.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.52	gold quality
bone marrow cell	CL:0002092	72.91	silver quality
cortical plate	UBERON:0005343	67.26	gold quality
corpus callosum	UBERON:0002336	66.31	gold quality
ventricular zone	UBERON:0003053	66.29	gold quality
stromal cell of endometrium	CL:0002255	66.18	gold quality
skeletal muscle tissue	UBERON:0001134	64.89	gold quality
bone marrow	UBERON:0002371	63.34	gold quality
prefrontal cortex	UBERON:0000451	63.06	gold quality
ganglionic eminence	UBERON:0004023	63.03	gold quality
liver	UBERON:0002107	61.82	gold quality
superior frontal gyrus	UBERON:0002661	60.49	gold quality
frontal cortex	UBERON:0001870	59.05	gold quality
right lobe of liver	UBERON:0001114	58.87	gold quality
lower esophagus mucosa	UBERON:0035834	58.62	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.49	gold quality
leukocyte	CL:0000738	57.97	gold quality
granulocyte	CL:0000094	57.84	gold quality
endometrium	UBERON:0001295	57.69	gold quality
right coronary artery	UBERON:0001625	57.59	gold quality
monocyte	CL:0000576	57.53	gold quality
primary visual cortex	UBERON:0002436	57.32	gold quality
nucleus accumbens	UBERON:0001882	57.29	gold quality
cerebral cortex	UBERON:0000956	56.83	gold quality
putamen	UBERON:0001874	56.76	gold quality
right ovary	UBERON:0002118	56.68	gold quality
caudate nucleus	UBERON:0001873	56.67	gold quality
vermiform appendix	UBERON:0001154	56.61	gold quality
Brodmann (1909) area 9	UBERON:0013540	56.60	gold quality
uterine cervix	UBERON:0000002	56.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.