RFX5-AS1

Summary

RFX5-AS1 (RFX5 antisense RNA 1, HGNC:40503) is a long non-coding RNA gene on chromosome 1q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40503
Approved symbol	RFX5-AS1
Name	RFX5 antisense RNA 1
Location	1q21.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	GBAT2
Ensembl gene	ENSG00000237976
Ensembl biotype	lncRNA
Entrez	101927886
RNAcentral	URS00008E3A53 — lncRNA, 449 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000455503, ENST00000609583, ENST00000811547, ENST00000811548, ENST00000811647

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000455503 — 2 exons

Exon	Start	End
ENSE00004209797	151346888	151347188
ENSE00004209798	151347632	151348027

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 93.55.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.8253 / max 150.2202, expressed in 1073 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
5225	1.8488	738
5224	0.9765	510

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.55	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.77	gold quality
bone marrow cell	CL:0002092	76.07	gold quality
ganglionic eminence	UBERON:0004023	75.64	gold quality
ventricular zone	UBERON:0003053	74.23	gold quality
cortical plate	UBERON:0005343	70.89	gold quality
tibialis anterior	UBERON:0001385	70.63	silver quality
granulocyte	CL:0000094	70.35	gold quality
leukocyte	CL:0000738	70.07	gold quality
monocyte	CL:0000576	69.74	gold quality
right adrenal gland cortex	UBERON:0035827	69.56	gold quality
bone marrow	UBERON:0002371	69.53	gold quality
colonic epithelium	UBERON:0000397	69.36	silver quality
stromal cell of endometrium	CL:0002255	68.40	gold quality
sperm	CL:0000019	68.22	gold quality
amygdala	UBERON:0001876	67.80	gold quality
right adrenal gland	UBERON:0001233	67.40	gold quality
left adrenal gland cortex	UBERON:0035825	67.39	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	67.38	gold quality
left adrenal gland	UBERON:0001234	67.01	gold quality
lymph node	UBERON:0000029	66.96	gold quality
hypothalamus	UBERON:0001898	66.84	gold quality
prefrontal cortex	UBERON:0000451	66.82	gold quality
adrenal cortex	UBERON:0001235	66.75	gold quality
putamen	UBERON:0001874	66.73	gold quality
anterior cingulate cortex	UBERON:0009835	66.42	gold quality
ileal mucosa	UBERON:0000331	66.34	gold quality
spinal cord	UBERON:0002240	66.33	gold quality
nucleus accumbens	UBERON:0001882	66.12	gold quality
vermiform appendix	UBERON:0001154	65.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.