RGS2-AS1

Summary

RGS2-AS1 (RSG2 antisense RNA 1, HGNC:49018) is a long non-coding RNA gene on chromosome 1q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49018
Approved symbol	RGS2-AS1
Name	RSG2 antisense RNA 1
Location	1q31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000285280
Ensembl biotype	lncRNA
Entrez	102724954
RNAcentral	URS00007E4373 — lncRNA, 435 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 55 — 55 lncRNA

ENST00000434300, ENST00000451690, ENST00000642855, ENST00000643151, ENST00000644058, ENST00000644134, ENST00000644436, ENST00000644504, ENST00000645822, ENST00000646471, ENST00000646606, ENST00000646999, ENST00000647436, ENST00000655304, ENST00000657453, ENST00000737306, ENST00000737307, ENST00000737308, ENST00000737309, ENST00000737310, ENST00000737311, ENST00000737312, ENST00000737313, ENST00000737314, ENST00000737315, ENST00000737316, ENST00000737317, ENST00000737318, ENST00000737319, ENST00000737320, ENST00000737321, ENST00000737322, ENST00000737323, ENST00000737324, ENST00000737325, ENST00000753761, ENST00000818440, ENST00000818441, ENST00000818442, ENST00000818443, ENST00000818444, ENST00000818445, ENST00000818446, ENST00000818447, ENST00000818448, ENST00000818449, ENST00000818450, ENST00000818451, ENST00000818452, ENST00000818453, ENST00000818454, ENST00000818455, ENST00000818456, ENST00000818457, ENST00000818458

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434300 — 4 exons

Exon	Start	End
ENSE00001642232	192567147	192567216
ENSE00003827407	192593599	192593657
ENSE00004071465	192739391	192739495
ENSE00004071483	192516588	192517963

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 89.37.

Top tissues by expression

136 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	89.37	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.36	gold quality
granulocyte	CL:0000094	82.74	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.33	gold quality
calcaneal tendon	UBERON:0003701	74.82	gold quality
skeletal muscle tissue	UBERON:0001134	72.99	gold quality
cerebellar vermis	UBERON:0004720	72.98	gold quality
bone marrow cell	CL:0002092	72.62	gold quality
testis	UBERON:0000473	72.58	gold quality
left testis	UBERON:0004533	72.25	gold quality
sural nerve	UBERON:0015488	72.11	gold quality
right testis	UBERON:0004534	71.91	gold quality
apex of heart	UBERON:0002098	70.73	gold quality
mucosa of stomach	UBERON:0001199	70.62	gold quality
muscle tissue	UBERON:0002385	69.81	gold quality
lower esophagus muscularis layer	UBERON:0035833	69.60	gold quality
lower esophagus	UBERON:0013473	69.55	gold quality
bone marrow	UBERON:0002371	69.07	gold quality
muscle of leg	UBERON:0001383	68.81	gold quality
blood	UBERON:0000178	68.77	gold quality
leukocyte	CL:0000738	68.69	gold quality
monocyte	CL:0000576	68.32	gold quality
gastrocnemius	UBERON:0001388	68.26	gold quality
skin of leg	UBERON:0001511	68.16	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	67.77	gold quality
colonic epithelium	UBERON:0000397	67.58	gold quality
cerebellar hemisphere	UBERON:0002245	67.58	gold quality
cerebellar cortex	UBERON:0002129	67.55	gold quality
cerebellum	UBERON:0002037	67.47	gold quality
lower esophagus mucosa	UBERON:0035834	67.37	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	18.01
E-ANND-3	yes	6.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.