RHOA-IT1

Summary

RHOA-IT1 (RHOA intronic transcript 1, HGNC:41308) is a long non-coding RNA gene on chromosome 3p21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41308
Approved symbol	RHOA-IT1
Name	RHOA intronic transcript 1
Location	3p21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235908
Ensembl biotype	lncRNA
Entrez	106480739
RNAcentral	URS000030294E — lncRNA, 517 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000428083

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428083 — 2 exons

Exon	Start	End
ENSE00001536670	49365145	49365224
ENSE00001773751	49366570	49367006

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 80.68.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	80.68	gold quality
colonic epithelium	UBERON:0000397	75.74	gold quality
bone marrow	UBERON:0002371	75.68	gold quality
monocyte	CL:0000576	70.17	gold quality
leukocyte	CL:0000738	69.36	gold quality
ganglionic eminence	UBERON:0004023	68.78	gold quality
stromal cell of endometrium	CL:0002255	68.59	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.35	gold quality
blood	UBERON:0000178	67.92	gold quality
ectocervix	UBERON:0012249	67.75	gold quality
ventricular zone	UBERON:0003053	67.64	gold quality
uterine cervix	UBERON:0000002	67.29	gold quality
right ovary	UBERON:0002118	67.21	gold quality
skeletal muscle tissue	UBERON:0001134	67.00	gold quality
ovary	UBERON:0000992	66.34	gold quality
left ovary	UBERON:0002119	66.32	gold quality
mucosa of stomach	UBERON:0001199	66.17	gold quality
upper lobe of left lung	UBERON:0008952	65.77	gold quality
lymph node	UBERON:0000029	65.59	gold quality
vagina	UBERON:0000996	65.58	gold quality
lung	UBERON:0002048	65.50	gold quality
body of uterus	UBERON:0009853	65.22	gold quality
myometrium	UBERON:0001296	65.19	gold quality
popliteal artery	UBERON:0002250	64.71	gold quality
tibial artery	UBERON:0007610	64.68	gold quality
skin of abdomen	UBERON:0001416	64.62	gold quality
descending thoracic aorta	UBERON:0002345	64.44	gold quality
urinary bladder	UBERON:0001255	63.93	gold quality
tonsil	UBERON:0002372	63.84	gold quality
tibial nerve	UBERON:0001323	63.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.