RHOBTB2-AS1

Summary

RHOBTB2-AS1 (RHOBTB2 antisense RNA 1, HGNC:58239) is a long non-coding RNA gene on chromosome 8p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58239
Approved symbol	RHOBTB2-AS1
Name	RHOBTB2 antisense RNA 1
Location	8p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245025
Ensembl biotype	lncRNA
Entrez	107984124
RNAcentral	URS0000EF16BB — lncRNA, 4918 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000502083, ENST00000523884, ENST00000665917, ENST00000754420

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502083 — 2 exons

Exon	Start	End
ENSE00001970641	23006381	23008117
ENSE00001980796	23019128	23019335

Expression profiles

Bgee: expression breadth ubiquitous, 163 present calls, max score 77.94.

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.94	gold quality
mucosa of stomach	UBERON:0001199	77.64	gold quality
body of uterus	UBERON:0009853	77.55	gold quality
smooth muscle tissue	UBERON:0001135	77.17	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	76.54	gold quality
left uterine tube	UBERON:0001303	76.47	gold quality
granulocyte	CL:0000094	76.42	gold quality
lower esophagus muscularis layer	UBERON:0035833	75.97	gold quality
lower esophagus	UBERON:0013473	75.88	gold quality
left ovary	UBERON:0002119	75.07	gold quality
right ovary	UBERON:0002118	74.88	gold quality
bone marrow cell	CL:0002092	74.77	gold quality
left adrenal gland cortex	UBERON:0035825	73.67	gold quality
right adrenal gland cortex	UBERON:0035827	73.55	gold quality
upper lobe of left lung	UBERON:0008952	73.50	gold quality
left adrenal gland	UBERON:0001234	73.47	gold quality
muscle layer of sigmoid colon	UBERON:0035805	73.29	gold quality
colonic epithelium	UBERON:0000397	73.27	gold quality
right adrenal gland	UBERON:0001233	73.10	gold quality
hindlimb stylopod muscle	UBERON:0004252	72.77	gold quality
tibial nerve	UBERON:0001323	72.09	gold quality
stromal cell of endometrium	CL:0002255	71.88	gold quality
adrenal gland	UBERON:0002369	71.77	gold quality
adrenal cortex	UBERON:0001235	71.58	gold quality
upper lobe of lung	UBERON:0008948	71.55	gold quality
endocervix	UBERON:0000458	71.19	gold quality
right lung	UBERON:0002167	71.06	gold quality
right coronary artery	UBERON:0001625	70.75	gold quality
ovary	UBERON:0000992	70.72	gold quality
popliteal artery	UBERON:0002250	70.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.56

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.