RHOXF1-AS1

Summary

RHOXF1-AS1 (RHOXF1 antisense RNA 1, HGNC:51582) is a long non-coding RNA gene on chromosome Xq24.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51582
Approved symbol	RHOXF1-AS1
Name	RHOXF1 antisense RNA 1
Location	Xq24
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258545
Ensembl biotype	lncRNA
Entrez	101928969
RNAcentral	URS0000812161 — lncRNA, 2120 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000553843, ENST00000555831, ENST00000557073, ENST00000665317, ENST00000687648, ENST00000829532, ENST00000829533

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553843 — 5 exons

Exon	Start	End
ENSE00002447501	120036236	120036532
ENSE00002453150	120143723	120143900
ENSE00002468016	120138998	120139119
ENSE00002506997	120145638	120146854
ENSE00002531107	120120852	120121139

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 85.15.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4770 / max 42.3357, expressed in 158 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
197417	0.3326	87
197415	0.1444	71

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lung	UBERON:0002167	85.15	gold quality
hindlimb stylopod muscle	UBERON:0004252	81.84	gold quality
right uterine tube	UBERON:0001302	81.30	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.22	gold quality
upper lobe of left lung	UBERON:0008952	79.46	gold quality
left lobe of thyroid gland	UBERON:0001120	78.91	gold quality
thyroid gland	UBERON:0002046	78.18	gold quality
lung	UBERON:0002048	77.19	gold quality
colonic epithelium	UBERON:0000397	76.84	gold quality
right lobe of thyroid gland	UBERON:0001119	76.11	gold quality
granulocyte	CL:0000094	74.53	gold quality
subcutaneous adipose tissue	UBERON:0002190	74.29	gold quality
thoracic mammary gland	UBERON:0005200	74.15	gold quality
skeletal muscle tissue	UBERON:0001134	74.00	gold quality
urinary bladder	UBERON:0001255	73.77	gold quality
adipose tissue	UBERON:0001013	73.75	gold quality
omental fat pad	UBERON:0010414	72.81	gold quality
muscle tissue	UBERON:0002385	71.18	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.08	gold quality
cerebellar hemisphere	UBERON:0002245	70.47	gold quality
cerebellar cortex	UBERON:0002129	70.43	gold quality
fallopian tube	UBERON:0003889	70.43	gold quality
cerebellum	UBERON:0002037	70.26	gold quality
body of pancreas	UBERON:0001150	69.79	gold quality
minor salivary gland	UBERON:0001830	69.50	gold quality
saliva-secreting gland	UBERON:0001044	68.92	gold quality
gastrocnemius	UBERON:0001388	68.89	gold quality
muscle of leg	UBERON:0001383	68.80	gold quality
esophagus mucosa	UBERON:0002469	68.65	gold quality
left ovary	UBERON:0002119	68.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.