RIPOR1

Summary

RIPOR1 (RHO family interacting cell polarization regulator 1, HGNC:25836) is a protein-coding gene on chromosome 16q22.1, encoding Rho family-interacting cell polarization regulator 1 (Q6ZS17). Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration.

Enables 14-3-3 protein binding activity. Involved in several processes, including establishment of Golgi localization; negative regulation of Rho guanyl-nucleotide exchange factor activity; and negative regulation of Rho protein signal transduction. Located in several cellular components, including Golgi apparatus; cell leading edge; and cytosol.

Source: NCBI Gene 79567 — RefSeq curated summary.

At a glance

• GWAS associations: 4
• Clinical variants (ClinVar): 200 total
• MANE Select transcript: NM_024519

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:25836
Approved symbol	RIPOR1
Name	RHO family interacting cell polarization regulator 1
Location	16q22.1
Locus type	gene with protein product
Status	Approved
Aliases	FLJ13725
Ensembl gene	ENSG00000039523
Ensembl biotype	protein_coding
OMIM	619842
Entrez	79567

Gene structure

Transcript identifiers

Ensembl transcripts: 40 — 31 protein_coding, 7 retained_intron, 1 protein_coding_CDS_not_defined, 1 nonsense_mediated_decay

ENST00000042381, ENST00000379312, ENST00000422602, ENST00000428437, ENST00000540839, ENST00000561534, ENST00000562116, ENST00000562755, ENST00000564616, ENST00000565176, ENST00000565190, ENST00000565679, ENST00000566522, ENST00000566559, ENST00000566730, ENST00000566815, ENST00000566907, ENST00000566920, ENST00000568959, ENST00000569179, ENST00000569253, ENST00000569474, ENST00000569733, ENST00000860989, ENST00000860990, ENST00000860991, ENST00000860992, ENST00000860993, ENST00000860994, ENST00000860995, ENST00000860996, ENST00000860997, ENST00000860998, ENST00000860999, ENST00000861000, ENST00000861001, ENST00000861002, ENST00000861003, ENST00000965781, ENST00000965782

RefSeq mRNA: 5 — MANE Select: NM_024519 NM_001193522, NM_001193523, NM_001193524, NM_001410885, NM_024519

CCDS: CCDS10840, CCDS54026, CCDS54027, CCDS54028, CCDS92176

Canonical transcript exons

ENST00000042381 — 22 exons

Exon	Start	End
ENSE00001380181	67528829	67528914
ENSE00003505157	67546366	67546786
ENSE00003539957	67538424	67538550
ENSE00003801384	67540300	67540363
ENSE00003801433	67544956	67545117
ENSE00003801861	67539846	67539899
ENSE00003803162	67545664	67545860
ENSE00003803502	67540579	67540704
ENSE00003803768	67543348	67543469
ENSE00003804977	67539728	67539751
ENSE00003805247	67540053	67540205
ENSE00003805827	67545376	67545534
ENSE00003805966	67544299	67544431
ENSE00003806300	67540458	67540501
ENSE00003806516	67546141	67546231
ENSE00003806764	67538990	67539068
ENSE00003806783	67541430	67541578
ENSE00003806883	67541653	67541782
ENSE00003807048	67545949	67546032
ENSE00003807054	67538672	67538824
ENSE00003809764	67541867	67543264
ENSE00003810335	67544695	67544830

Expression profiles

Bgee: expression breadth ubiquitous, 274 present calls, max score 97.83.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 30.5908 / max 908.5516, expressed in 1805 samples.

FANTOM5 promoters (11 alternative TSS)

Promoter ID	TPM avg	Samples expressed
154641	19.8221	1778
154645	6.0305	1350
154654	2.1436	916
154655	1.1631	463
154656	0.9720	359
154657	0.3136	109
154643	0.0534	9
154639	0.0371	9
154642	0.0308	12
154640	0.0167	6

Top tissues by expression

288 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
apex of heart	UBERON:0002098	97.83	gold quality
right lung	UBERON:0002167	97.50	gold quality
upper lobe of left lung	UBERON:0008952	96.63	gold quality
renal glomerulus	UBERON:0000074	96.53	gold quality
spleen	UBERON:0002106	96.47	gold quality
right hemisphere of cerebellum	UBERON:0014890	96.46	gold quality
metanephric glomerulus	UBERON:0004736	96.28	gold quality
right coronary artery	UBERON:0001625	96.22	gold quality
right frontal lobe	UBERON:0002810	96.19	gold quality
upper lobe of lung	UBERON:0008948	96.17	gold quality
metanephros cortex	UBERON:0010533	96.07	gold quality
cerebellar hemisphere	UBERON:0002245	96.03	gold quality
cerebellar cortex	UBERON:0002129	95.98	gold quality
ascending aorta	UBERON:0001496	95.78	gold quality
cortical plate	UBERON:0005343	95.74	gold quality
thoracic aorta	UBERON:0001515	95.73	gold quality
body of uterus	UBERON:0009853	95.73	gold quality
left uterine tube	UBERON:0001303	95.68	gold quality
omental fat pad	UBERON:0010414	95.51	gold quality
sural nerve	UBERON:0015488	95.49	gold quality
peritoneum	UBERON:0002358	95.47	gold quality
lower esophagus muscularis layer	UBERON:0035833	95.43	gold quality
lower esophagus	UBERON:0013473	95.41	gold quality
descending thoracic aorta	UBERON:0002345	95.38	gold quality
aorta	UBERON:0000947	95.31	gold quality
left coronary artery	UBERON:0001626	95.28	gold quality
cortex of kidney	UBERON:0001225	95.25	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	95.22	gold quality
endocervix	UBERON:0000458	95.19	gold quality
mucosa of stomach	UBERON:0001199	95.17	gold quality

Single-cell (SCXA)

Detected in 4 experiment(s), a significant marker in 3.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	28.50
E-ANND-3	yes	12.95
E-MTAB-9543	yes	7.72
E-CURD-112	no	2.72

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

38 targeting RIPOR1, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-3163	100.00	77.23	8605
HSA-MIR-656-3P	100.00	72.15	2788
HSA-MIR-5692A	100.00	74.40	6850
HSA-MIR-1277-5P	100.00	73.95	5056
HSA-MIR-3686	99.90	70.53	2432
HSA-MIR-345-3P	99.89	70.23	1421
HSA-MIR-3140-3P	99.88	68.47	2069
HSA-MIR-3151-5P	99.86	63.83	1069
HSA-MIR-4447	99.85	67.81	2900
HSA-MIR-4728-5P	99.85	69.39	4718
HSA-MIR-6785-5P	99.82	68.68	4428
HSA-MIR-4760-5P	99.80	69.88	1619
HSA-MIR-6885-3P	99.75	70.36	3187
HSA-MIR-6752-3P	99.72	66.71	1587
HSA-MIR-1825	99.72	68.11	1089
HSA-MIR-149-3P	99.72	68.22	3963
HSA-MIR-6883-5P	99.69	68.05	3785
HSA-MIR-8061	99.63	69.44	1411
HSA-MIR-4663	99.62	65.33	957
HSA-MIR-4472	99.56	66.08	1478
HSA-MIR-4688	99.48	64.68	828
HSA-MIR-6743-5P	99.48	63.60	721
HSA-MIR-6507-5P	99.36	70.46	2524
HSA-MIR-4505	99.27	67.81	2678
HSA-MIR-10522-5P	99.26	68.50	2087
HSA-MIR-5787	99.22	67.86	2628
HSA-MIR-491-5P	99.13	65.98	1468
HSA-MIR-6809-5P	99.13	68.45	1223
HSA-MIR-3688-5P	99.12	69.67	1091
HSA-MIR-4764-5P	98.88	65.53	894

Literature-anchored findings (GeneRIF, showing 1)

• These results reveal a previously unidentified pathway downstream of RHO that regulates the polarity of migrating cells through Golgi reorientation in a FAM65A-, CCM3- and MST3- and MST4-dependent manner. (PMID:27807006)

Cross-species orthologs

4 orthologs

Organism	Symbol	Gene ID
danio_rerio	ripor1	ENSDARG00000062178
mus_musculus	Ripor1	ENSMUSG00000038604
rattus_norvegicus	Ripor1	ENSRNOG00000017604
caenorhabditis_elegans		WBGENE00045063

Paralogs (2): RIPOR3 (ENSG00000042062), RIPOR2 (ENSG00000111913)

Protein

Protein identifiers

Rho family-interacting cell polarization regulator 1 — Q6ZS17 (reviewed: Q6ZS17)

All UniProt accessions (12): A0A0A0MTL6, A0A0G2JLA4, Q6ZS17, H3BMG9, H3BP86, H3BQI5, H3BS40, H3BSV5, H3BSX9, H3BU12, H3BUP6, H3BV02

UniProt curated annotations — full annotation on UniProt →

Function. Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation.

Subunit / interactions. Interacts (via N-terminus) with RHOA (GTP-bound form); this interaction links active RHOA to STK24 and STK26 kinases. Interacts with RHOB. Interacts with RHOC. Interacts (via C-terminus) with PDCD10; this interaction occurs in a Rho-independent manner. Interacts (via C-terminus) with STK24; this interaction occurs in a PDCD10-dependent and Rho-independent manner. Interacts (via C-terminus) with STK26; this interaction occurs in a PDCD10-dependent and Rho-independent manner. Interacts (via N-terminus) with 14-3-3 proteins; these interactions occur in a Rho-dependent manner.

Subcellular location. Cytoplasm. Golgi apparatus.

Similarity. Belongs to the RIPOR family.

Isoforms (4)

UniProt ID	Names	Canonical?
Q6ZS17-1	1	yes
Q6ZS17-2	2
Q6ZS17-3	3
Q6ZS17-4	4

RefSeq proteins (5): NP_001180451, NP_001180452, NP_001180453, NP_001397814, NP_078795* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR011989	ARM-like	Homologous_superfamily
IPR016024	ARM-type_fold	Homologous_superfamily
IPR026136	RIPOR3	Family
IPR031780	FAM65_N	Domain

Pfam: PF15903

UniProt features (29 total): compositionally biased region 8, modified residue 8, sequence conflict 5, region of interest 3, splice variant 3, chain 1, coiled-coil region 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q6ZS17-F1	63.47	0.33

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (8): 22, 349, 351, 355, 456, 459, 874, 875

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 231 (showing top): ATF_B, WANG_CLIM2_TARGETS_UP, chr16q22, GOBP_INTRACELLULAR_PROTEIN_TRANSPORT, GOBP_RESPONSE_TO_PEPTIDE, RORA1_01, GOBP_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT, GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP, GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP, GOBP_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION, GOBP_REGULATION_OF_GTPASE_ACTIVITY, GOBP_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION, AP4_Q6, MEF2_02, GGGTGGRR_PAX4_03

GO Biological Process (10): Rho protein signal transduction (GO:0007266), cellular response to starvation (GO:0009267), response to wounding (GO:0009611), positive regulation of cell migration (GO:0030335), protein localization to Golgi apparatus (GO:0034067), negative regulation of Rho protein signal transduction (GO:0035024), establishment of Golgi localization (GO:0051683), positive regulation of intracellular protein transport (GO:0090316), cellular response to chemokine (GO:1990869), negative regulation of Rho guanyl-nucleotide exchange factor activity (GO:2001107)

GO Molecular Function (2): 14-3-3 protein binding (GO:0071889), protein binding (GO:0005515)

GO Cellular Component (7): cytoplasm (GO:0005737), Golgi apparatus (GO:0005794), cytosol (GO:0005829), vesicle membrane (GO:0012506), membrane (GO:0016020), cell leading edge (GO:0031252), extracellular exosome (GO:0070062)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
cellular anatomical structure	4
cytoplasm	2
small GTPase-mediated signal transduction	1
cellular response to nutrient levels	1
cellular response to stress	1
response to starvation	1
response to stress	1
cell migration	1
regulation of cell migration	1
positive regulation of cell motility	1
protein localization to organelle	1
Rho protein signal transduction	1
regulation of Rho protein signal transduction	1
negative regulation of small GTPase mediated signal transduction	1
Golgi localization	1
establishment of localization in cell	1
establishment of organelle localization	1
intracellular protein transport	1
positive regulation of intracellular transport	1
regulation of intracellular protein transport	1
positive regulation of protein transport	1
cellular response to cytokine stimulus	1
response to chemokine	1
negative regulation of guanyl-nucleotide exchange factor activity	1
protein binding	1
binding	1
intracellular anatomical structure	1
endomembrane system	1
intracellular membrane-bounded organelle	1
organelle membrane	1
vesicle	1
extracellular vesicle	1

Protein interactions and networks

STRING

1010 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
RIPOR1	RHOC	P08134	731
RIPOR1	RHOB	P01121	712
RIPOR1	RHOA	P06749	562
RIPOR1	R3HDM2	Q9Y2K5	485
RIPOR1	STK26	Q9P289	482
RIPOR1	C16orf86	Q6ZW13	472
RIPOR1	STRN	O43815	469
RIPOR1	PDCD10	Q9BUL8	446
RIPOR1	STRIP1	Q5VSL9	426
RIPOR1	NPEPL1	Q8NDH3	417
RIPOR1	NAA20	P61599	410
RIPOR1	STK25	O00506	409
RIPOR1	STRIP2	Q9ULQ0	401
RIPOR1	LY6G5C	Q5SRR4	397
RIPOR1	CRNKL1	Q9BZJ0	390

IntAct

16 interactions, top by confidence:

A	B	Type	Score
RHOC	RAP1GDS1	psi-mi:“MI:0914”(association)	0.730
YWHAB	PLEKHG3	psi-mi:“MI:0914”(association)	0.480
	RIPOR1	psi-mi:“MI:0915”(physical association)	0.400
MAP1LC3B	RIPOR1	psi-mi:“MI:0915”(physical association)	0.370
	RIPOR1	psi-mi:“MI:0915”(physical association)	0.370
Xpo1	IFT56	psi-mi:“MI:0914”(association)	0.350
M		psi-mi:“MI:0914”(association)	0.350
RHOA	TAX1BP3	psi-mi:“MI:0914”(association)	0.350
RIPOR1	STK25	psi-mi:“MI:0914”(association)	0.350
CREB3L2	PLEKHG3	psi-mi:“MI:0914”(association)	0.350
PPP2R2B	ARHGAP10	psi-mi:“MI:0914”(association)	0.350
RIPOR1	MYO7A	psi-mi:“MI:0915”(physical association)	0.000
FMR1	RIPOR1	psi-mi:“MI:0915”(physical association)	0.000
RIPOR1	purCD	psi-mi:“MI:0915”(physical association)	0.000

BioGRID (25): FAM65A (Affinity Capture-MS), MYO7A (Affinity Capture-MS), FAM65A (Affinity Capture-RNA), FAM65A (Affinity Capture-RNA), FAM65A (Affinity Capture-RNA), PDCD10 (Affinity Capture-MS), STK25 (Affinity Capture-MS), STK26 (Affinity Capture-MS), MPP5 (Affinity Capture-MS), STK24 (Affinity Capture-MS), FAM65A (Affinity Capture-MS), FAM65A (Affinity Capture-MS), FAM65A (Affinity Capture-MS), FAM65A (Affinity Capture-MS), FAM65A (Affinity Capture-RNA)

ESM2 similar proteins: A1L3I3, A2AWH2, A2BDP1, A4IFM1, A4IHZ3, A5A6P7, A7E2V4, B1AL88, F1N4E5, O14525, O35181, O75949, O94901, O94983, P13265, P51654, P56975, P78333, Q07105, Q0VCT2, Q29016, Q2F7Z7, Q3T0Q2, Q3V140, Q4FZU8, Q4R8C8, Q5HZE8, Q5PQX1, Q5R7A3, Q5R800, Q60485, Q61137, Q68FE6, Q6H9L7, Q6P7B4, Q6V9Y8, Q6ZS17, Q7TNI2, Q80Y50, Q8BHP7

Diamond homologs: A1L3T7, A9ZLX4, Q1LU99, Q3B7M3, Q4FZU8, Q5EB20, Q5F3L9, Q68FE6, Q6ZS17, Q7TP54, Q80U16, Q96MK2, Q9Y4F9

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

200 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	165
Likely benign	10
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

3306 predictions. Top by Δscore:

Variant	Effect	Δscore
16:67528910:GCCAT:G	donor_gain	1.0000
16:67528915:G:GG	donor_gain	1.0000
16:67538547:CCAGG:C	donor_loss	1.0000
16:67538548:CAG:C	donor_loss	1.0000
16:67538549:AGGTA:A	donor_loss	1.0000
16:67538551:G:GC	donor_loss	1.0000
16:67538552:T:G	donor_loss	1.0000
16:67538822:GAC:G	donor_gain	1.0000
16:67538825:G:GG	donor_gain	1.0000
16:67538891:G:GT	donor_gain	1.0000
16:67539044:G:GT	donor_gain	1.0000
16:67539064:GCTTG:G	donor_gain	1.0000
16:67539718:A:AG	acceptor_gain	1.0000
16:67539719:C:G	acceptor_gain	1.0000
16:67539844:A:AG	acceptor_gain	1.0000
16:67539845:G:GG	acceptor_gain	1.0000
16:67539845:GCAA:G	acceptor_gain	1.0000
16:67539848:A:G	acceptor_gain	1.0000
16:67539895:GCAAG:G	donor_gain	1.0000
16:67539898:AGGT:A	donor_loss	1.0000
16:67539900:G:GA	donor_loss	1.0000
16:67539900:G:GG	donor_gain	1.0000
16:67539901:T:G	donor_loss	1.0000
16:67540043:A:AG	acceptor_gain	1.0000
16:67540044:C:G	acceptor_gain	1.0000
16:67540051:A:AG	acceptor_gain	1.0000
16:67540052:G:GA	acceptor_gain	1.0000
16:67540052:GATC:G	acceptor_gain	1.0000
16:67540202:GGAG:G	donor_gain	1.0000
16:67540203:GAGG:G	donor_gain	1.0000

AlphaMissense

7843 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
16:67540469:T:C	F219L	1.000
16:67540471:C:A	F219L	1.000
16:67540471:C:G	F219L	1.000
16:67540473:C:A	A220D	1.000
16:67540606:T:A	W239R	1.000
16:67540606:T:C	W239R	1.000
16:67540648:T:A	W253R	1.000
16:67540648:T:C	W253R	1.000
16:67541557:T:C	L314P	1.000
16:67541563:T:C	L316P	1.000
16:67541574:T:A	W320R	1.000
16:67541574:T:C	W320R	1.000
16:67538809:T:C	L85P	0.999
16:67538821:T:C	L89P	0.999
16:67539028:T:C	L103P	0.999
16:67539744:T:C	L122P	0.999
16:67539880:T:C	L136P	0.999
16:67539885:T:C	F138L	0.999
16:67539887:C:A	F138L	0.999
16:67539887:C:G	F138L	0.999
16:67540346:T:C	F209S	0.999
16:67540466:G:C	G218R	0.999
16:67540467:G:A	G218D	0.999
16:67540479:T:C	L222P	0.999
16:67540496:T:C	Y228H	0.999
16:67540496:T:G	Y228D	0.999
16:67540613:T:C	L241P	0.999
16:67540618:G:C	G243R	0.999
16:67540619:G:A	G243D	0.999
16:67540650:G:C	W253C	0.999

dbSNP variants (sampled 300 via entrez): RS1000046238 (16:67517359 A>G), RS1000080601 (16:67519734 G>A), RS1000190522 (16:67532917 T>C), RS1000252707 (16:67524082 C>T), RS1000329784 (16:67536829 A>G), RS1000458619 (16:67529648 A>C), RS1000510276 (16:67531427 C>G), RS1000578530 (16:67531896 T>C,G), RS1000584742 (16:67522367 T>C), RS1000616170 (16:67535233 G>A,T), RS1000708740 (16:67531044 G>A,C), RS1000873662 (16:67539215 T>G), RS1001141901 (16:67537857 C>A,G,T), RS1001187947 (16:67528836 G>C,T), RS1001351597 (16:67522910 G>C)

Disease associations

OMIM: gene MIM:619842 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

4 associations (top):

Study	Trait	p-value
GCST006979_628	Heel bone mineral density	5.000000e-15
GCST010002_113	Refractive error	2.000000e-14
GCST010083_158	Hemoglobin levels	1.000000e-10
GCST90002388_169	Lymphocyte count	7.000000e-11

EFO canonical traits (3, from GWAS)

EFO ID	Trait name
EFO:0009270	heel bone mineral density
EFO:0004509	hemoglobin measurement
EFO:0004587	lymphocyte count

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

30 total (human), top 30 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Arsenic	affects methylation, increases abundance, increases expression	2
aristolochic acid I	increases expression	1
FR900359	increases phosphorylation	1
dicrotophos	increases expression	1
triphenyl phosphate	affects expression	1
bisphenol A	decreases methylation	1
lead acetate	increases expression	1
sodium arsenate	increases abundance, increases expression	1
ethyl-p-hydroxybenzoate	increases expression	1
beta-lapachone	increases expression	1
beta-methylcholine	affects expression	1
ICG 001	increases expression	1
Decitabine	affects expression	1
Sunitinib	increases expression	1
Leflunomide	increases expression	1
Acetaminophen	increases expression	1
Cadmium	decreases expression, increases abundance	1
Caffeine	affects phosphorylation	1
Calcitriol	decreases expression	1
Cisplatin	affects expression	1
Doxorubicin	decreases expression	1
Rotenone	decreases expression	1
Silicon Dioxide	increases expression	1
Tetrachlorodibenzodioxin	increases expression	1
Valproic Acid	affects expression	1
Vanadates	increases expression	1
Cyclosporine	increases expression	1
Aflatoxin B1	increases methylation	1
Sodium Selenite	increases expression	1
Cadmium Chloride	decreases expression, increases abundance	1

Cellosaurus cell lines

1 cell lines: 1 cancer cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_B2DV	Abcam HeLa RIPOR1 KO	Cancer cell line	Female

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.