RNASEH1-DT

Summary

RNASEH1-DT (RNASEH1 divergent transcript, HGNC:49289) is a long non-coding RNA gene on chromosome 2p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49289
Approved symbol	RNASEH1-DT
Name	RNASEH1 divergent transcript
Location	2p25.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	LOC100506054
Ensembl gene	ENSG00000234171
Ensembl biotype	lncRNA
Entrez	100506054
RNAcentral	URS000075E8BB — lncRNA, 1329 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000426725, ENST00000438436, ENST00000664922, ENST00000797888, ENST00000797889, ENST00000797890, ENST00000797891, ENST00000797892

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000426725 — 2 exons

Exon	Start	End
ENSE00004184936	3561317	3561739
ENSE00004184943	3558375	3558998

Expression profiles

Bgee: expression breadth ubiquitous, 186 present calls, max score 82.76.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.6555 / max 91.0143, expressed in 1719 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
18631	3.4765	1220
18629	2.9251	1300
18630	1.2539	948

Top tissues by expression

238 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	82.76	gold quality
spinal cord	UBERON:0002240	80.31	gold quality
endothelial cell	CL:0000115	79.52	gold quality
amygdala	UBERON:0001876	78.75	gold quality
apex of heart	UBERON:0002098	78.41	gold quality
anterior cingulate cortex	UBERON:0009835	77.99	gold quality
hypothalamus	UBERON:0001898	77.97	gold quality
substantia nigra	UBERON:0002038	77.88	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.87	gold quality
granulocyte	CL:0000094	77.63	gold quality
buccal mucosa cell	CL:0002336	77.38	gold quality
putamen	UBERON:0001874	76.98	gold quality
calcaneal tendon	UBERON:0003701	76.93	gold quality
prefrontal cortex	UBERON:0000451	76.84	gold quality
adenohypophysis	UBERON:0002196	76.56	gold quality
stromal cell of endometrium	CL:0002255	76.44	gold quality
tendon	UBERON:0000043	76.25	gold quality
muscle of leg	UBERON:0001383	76.20	gold quality
gastrocnemius	UBERON:0001388	75.92	gold quality
right adrenal gland	UBERON:0001233	75.88	gold quality
Brodmann (1909) area 9	UBERON:0013540	75.87	gold quality
metanephros cortex	UBERON:0010533	75.72	gold quality
right frontal lobe	UBERON:0002810	75.66	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.56	gold quality
nucleus accumbens	UBERON:0001882	75.51	gold quality
pituitary gland	UBERON:0000007	75.46	gold quality
tibial artery	UBERON:0007610	75.40	gold quality
popliteal artery	UBERON:0002250	75.38	gold quality
lower esophagus muscularis layer	UBERON:0035833	75.38	gold quality
right coronary artery	UBERON:0001625	75.36	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.