RNF139-DT

Summary

RNF139-DT (RNF139 divergent transcript, HGNC:48940) is a long non-coding RNA gene on chromosome 8q24.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48940
Approved symbol	RNF139-DT
Name	RNF139 divergent transcript
Location	8q24.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245149
Ensembl biotype	lncRNA
Entrez	101927612
RNAcentral	URS000075CCEF — lncRNA, 5658 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000499418, ENST00000519861, ENST00000530778, ENST00000669597, ENST00000690375, ENST00000693326, ENST00000778841, ENST00000778842, ENST00000778843, ENST00000778844, ENST00000778845, ENST00000778846, ENST00000778847, ENST00000778848, ENST00000778849, ENST00000778850, ENST00000778851, ENST00000778852

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499418 — 2 exons

Exon	Start	End
ENSE00001980182	124462485	124467658
ENSE00001990366	124474085	124474564

Expression profiles

Bgee: expression breadth ubiquitous, 166 present calls, max score 79.45.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.0486 / max 50.0734, expressed in 1359 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
94753	3.5702	1234
94752	0.4784	235

Top tissues by expression

251 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	79.45	gold quality
adenohypophysis	UBERON:0002196	78.54	gold quality
pituitary gland	UBERON:0000007	78.11	gold quality
right hemisphere of cerebellum	UBERON:0014890	75.93	gold quality
left ovary	UBERON:0002119	75.80	gold quality
left lobe of thyroid gland	UBERON:0001120	75.76	gold quality
right ovary	UBERON:0002118	75.65	gold quality
right testis	UBERON:0004534	75.36	gold quality
sperm	CL:0000019	75.30	gold quality
cerebellar hemisphere	UBERON:0002245	75.30	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.10	gold quality
cerebellar cortex	UBERON:0002129	75.06	gold quality
left testis	UBERON:0004533	74.77	gold quality
right lobe of thyroid gland	UBERON:0001119	74.64	gold quality
tibial artery	UBERON:0007610	74.54	gold quality
popliteal artery	UBERON:0002250	74.53	gold quality
metanephros cortex	UBERON:0010533	74.49	gold quality
thyroid gland	UBERON:0002046	74.04	gold quality
right coronary artery	UBERON:0001625	73.76	gold quality
body of uterus	UBERON:0009853	73.63	gold quality
aorta	UBERON:0000947	73.55	gold quality
cerebellum	UBERON:0002037	73.14	gold quality
mucosa of transverse colon	UBERON:0004991	72.92	gold quality
bone marrow cell	CL:0002092	72.87	gold quality
ascending aorta	UBERON:0001496	72.85	gold quality
thoracic aorta	UBERON:0001515	72.70	gold quality
transverse colon	UBERON:0001157	72.62	gold quality
lower esophagus muscularis layer	UBERON:0035833	72.48	gold quality
lower esophagus	UBERON:0013473	72.45	gold quality
granulocyte	CL:0000094	72.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.39

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.