RNF157-AS1

Summary

RNF157-AS1 (RNF157 antisense RNA 1, HGNC:44127) is a long non-coding RNA gene on chromosome 17q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44127
Approved symbol	RNF157-AS1
Name	RNF157 antisense RNA 1
Location	17q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267128
Ensembl biotype	lncRNA
Entrez	100507218
RNAcentral	URS000075B72C — lncRNA, 2177 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000585542, ENST00000586627, ENST00000586661, ENST00000590137, ENST00000592748, ENST00000662723, ENST00000828684, ENST00000828685, ENST00000828686, ENST00000828687

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000585542 — 2 exons

Exon	Start	End
ENSE00002781293	76140581	76140680
ENSE00002877778	76153133	76153483

Expression profiles

Bgee: expression breadth ubiquitous, 165 present calls, max score 98.65.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4202 / max 17.9402, expressed in 171 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
162819	0.4202	171

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	98.65	gold quality
right uterine tube	UBERON:0001302	90.68	gold quality
left testis	UBERON:0004533	87.73	gold quality
right testis	UBERON:0004534	87.55	gold quality
testis	UBERON:0000473	84.73	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.44	gold quality
ventricular zone	UBERON:0003053	81.83	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.01	gold quality
islet of Langerhans	UBERON:0000006	78.69	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	77.10	gold quality
metanephros cortex	UBERON:0010533	76.68	gold quality
bronchial epithelial cell	CL:0002328	75.25	gold quality
right frontal lobe	UBERON:0002810	75.11	gold quality
anterior cingulate cortex	UBERON:0009835	75.05	gold quality
bronchus	UBERON:0002185	73.69	gold quality
fallopian tube	UBERON:0003889	72.46	gold quality
Brodmann (1909) area 9	UBERON:0013540	72.42	gold quality
oviduct epithelium	UBERON:0004804	72.38	gold quality
ganglionic eminence	UBERON:0004023	71.98	gold quality
pancreas	UBERON:0001264	71.85	gold quality
thyroid gland	UBERON:0002046	71.80	gold quality
nucleus accumbens	UBERON:0001882	71.78	gold quality
hypothalamus	UBERON:0001898	71.77	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.64	gold quality
gastrocnemius	UBERON:0001388	71.59	gold quality
cortical plate	UBERON:0005343	71.52	gold quality
seminal vesicle	UBERON:0000998	71.40	gold quality
amygdala	UBERON:0001876	71.15	gold quality
muscle of leg	UBERON:0001383	71.14	gold quality
caudate nucleus	UBERON:0001873	71.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.