RNF186-AS1

Summary

RNF186-AS1 (RNF186 antisense RNA 1, HGNC:41127) is a long non-coding RNA gene on chromosome 1p36.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41127
Approved symbol	RNF186-AS1
Name	RNF186 antisense RNA 1
Location	1p36.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235434
Ensembl biotype	lncRNA
Entrez	121847981
RNAcentral	URS00026A1E9C — lncRNA, 405 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000454736

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000454736 — 2 exons

Exon	Start	End
ENSE00001644991	19819243	19819502
ENSE00004192289	19814354	19814553

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 76.80.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.80	silver quality
bone marrow cell	CL:0002092	73.74	silver quality
adult mammalian kidney	UBERON:0000082	70.21	gold quality
kidney	UBERON:0002113	67.91	gold quality
monocyte	CL:0000576	64.49	gold quality
subcutaneous adipose tissue	UBERON:0002190	64.45	gold quality
mucosa of transverse colon	UBERON:0004991	62.09	gold quality
adipose tissue	UBERON:0001013	62.03	gold quality
substantia nigra	UBERON:0002038	61.00	gold quality
cortex of kidney	UBERON:0001225	60.67	gold quality
thoracic mammary gland	UBERON:0005200	60.66	gold quality
islet of Langerhans	UBERON:0000006	59.50	gold quality
pancreas	UBERON:0001264	58.96	gold quality
duodenum	UBERON:0002114	58.76	gold quality
omental fat pad	UBERON:0010414	58.65	gold quality
body of pancreas	UBERON:0001150	58.55	gold quality
liver	UBERON:0002107	55.85	gold quality
vermiform appendix	UBERON:0001154	55.46	gold quality
left adrenal gland cortex	UBERON:0035825	55.04	gold quality
colon	UBERON:0001155	54.64	gold quality
transverse colon	UBERON:0001157	54.56	gold quality
placenta	UBERON:0001987	53.97	gold quality
multicellular organism	UBERON:0000468	53.95	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.70	gold quality
blood	UBERON:0000178	53.13	gold quality
metanephros cortex	UBERON:0010533	52.77	gold quality
intestine	UBERON:0000160	52.43	gold quality
muscle layer of sigmoid colon	UBERON:0035805	51.27	gold quality
rectum	UBERON:0001052	50.68	gold quality
left coronary artery	UBERON:0001626	50.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.17

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.