RNF213-AS1

Summary

RNF213-AS1 (RNF213 antisense RNA 1, HGNC:54402) is a long non-coding RNA gene on chromosome 17q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54402
Approved symbol	RNF213-AS1
Name	RNF213 antisense RNA 1
Location	17q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263069
Ensembl biotype	lncRNA
Entrez	100294362
RNAcentral	URS000075E001 — lncRNA, 3699 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000572151, ENST00000573394, ENST00000575034, ENST00000613190, ENST00000667202

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000572151 — 2 exons

Exon	Start	End
ENSE00002655418	80414929	80415118
ENSE00002656609	80354437	80354815

Expression profiles

Bgee: expression breadth ubiquitous, 169 present calls, max score 84.31.

FANTOM5 (CAGE): breadth broad, TPM avg 2.0757 / max 78.6981, expressed in 759 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
168619	1.1622	572
168618	0.7248	302
168617	0.1888	102

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	84.31	gold quality
right uterine tube	UBERON:0001302	82.12	gold quality
sural nerve	UBERON:0015488	80.68	gold quality
adenohypophysis	UBERON:0002196	80.37	gold quality
pituitary gland	UBERON:0000007	79.91	gold quality
bone marrow cell	CL:0002092	79.48	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.64	gold quality
cortical plate	UBERON:0005343	75.28	gold quality
metanephros cortex	UBERON:0010533	75.12	gold quality
right lobe of thyroid gland	UBERON:0001119	74.94	gold quality
left lobe of thyroid gland	UBERON:0001120	74.67	gold quality
body of uterus	UBERON:0009853	73.92	gold quality
thyroid gland	UBERON:0002046	73.55	gold quality
ventricular zone	UBERON:0003053	73.37	gold quality
monocyte	CL:0000576	72.88	gold quality
stromal cell of endometrium	CL:0002255	72.54	gold quality
upper lobe of left lung	UBERON:0008952	72.49	gold quality
left ovary	UBERON:0002119	72.47	gold quality
endocervix	UBERON:0000458	72.40	gold quality
leukocyte	CL:0000738	72.16	gold quality
spleen	UBERON:0002106	71.82	gold quality
muscle layer of sigmoid colon	UBERON:0035805	71.77	gold quality
apex of heart	UBERON:0002098	71.74	gold quality
right ovary	UBERON:0002118	71.64	gold quality
upper lobe of lung	UBERON:0008948	71.64	gold quality
left adrenal gland cortex	UBERON:0035825	71.45	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	71.44	gold quality
ectocervix	UBERON:0012249	71.40	gold quality
lower esophagus	UBERON:0013473	71.13	gold quality
lower esophagus muscularis layer	UBERON:0035833	71.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.87

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.