RNF217-AS1

Summary

RNF217-AS1 (RNF217 antisense RNA 1, HGNC:50866) is a long non-coding RNA gene on chromosome 6q22.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50866
Approved symbol	RNF217-AS1
Name	RNF217 antisense RNA 1
Location	6q22.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	STL
Ensembl gene	ENSG00000236548
Ensembl biotype	lncRNA
OMIM	602532
Entrez	7955
RNAcentral	URS000075EEB1 — lncRNA, 5360 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 58 — 58 lncRNA

ENST00000439075, ENST00000655205, ENST00000656500, ENST00000657116, ENST00000658379, ENST00000658682, ENST00000662961, ENST00000663550, ENST00000663732, ENST00000663792, ENST00000663982, ENST00000664507, ENST00000664931, ENST00000666728, ENST00000687689, ENST00000689361, ENST00000803589, ENST00000803590, ENST00000803591, ENST00000803592, ENST00000803593, ENST00000803594, ENST00000803595, ENST00000803596, ENST00000803597, ENST00000803598, ENST00000803599, ENST00000803600, ENST00000803601, ENST00000803602, ENST00000803603, ENST00000803604, ENST00000803605, ENST00000803606, ENST00000803607, ENST00000803608, ENST00000803609, ENST00000803610, ENST00000803611, ENST00000803612, ENST00000803613, ENST00000803614, ENST00000803615, ENST00000803616, ENST00000803617, ENST00000803618, ENST00000803619, ENST00000803620, ENST00000803621, ENST00000803622, ENST00000803623, ENST00000803624, ENST00000803625, ENST00000803626, ENST00000803627, ENST00000803628, ENST00000803629, ENST00000803630

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439075 — 7 exons

Exon	Start	End
ENSE00001598204	124962823	124963039
ENSE00001626404	124945299	124945439
ENSE00001686503	124931696	124931738
ENSE00001696287	124909093	124912859
ENSE00001757714	124935008	124935117
ENSE00001763769	124920188	124920248
ENSE00001782395	124947931	124948098

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 75.38.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.0241 / max 101.9408, expressed in 1002 samples.

FANTOM5 promoters (9 alternative TSS)

Promoter ID	TPM avg	Samples expressed
75391	0.5405	306
75392	0.4088	216
75395	0.3174	138
75399	0.2992	105
75393	0.2762	135
75396	0.0809	17
75394	0.0703	11
75398	0.0223	6
75397	0.0087	2

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	75.38	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.51	silver quality
calcaneal tendon	UBERON:0003701	74.17	gold quality
muscle layer of sigmoid colon	UBERON:0035805	72.61	gold quality
tibial artery	UBERON:0007610	72.60	gold quality
popliteal artery	UBERON:0002250	72.57	gold quality
colonic epithelium	UBERON:0000397	72.28	gold quality
sural nerve	UBERON:0015488	72.27	gold quality
muscle of leg	UBERON:0001383	72.24	gold quality
gastrocnemius	UBERON:0001388	72.02	gold quality
aorta	UBERON:0000947	71.32	gold quality
bone marrow cell	CL:0002092	70.28	silver quality
ascending aorta	UBERON:0001496	70.26	gold quality
thoracic aorta	UBERON:0001515	70.07	gold quality
right coronary artery	UBERON:0001625	69.93	gold quality
left lobe of thyroid gland	UBERON:0001120	69.47	gold quality
descending thoracic aorta	UBERON:0002345	69.37	gold quality
left coronary artery	UBERON:0001626	69.12	gold quality
right lobe of thyroid gland	UBERON:0001119	68.67	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.54	gold quality
thyroid gland	UBERON:0002046	68.41	gold quality
coronary artery	UBERON:0001621	67.62	gold quality
mucosa of stomach	UBERON:0001199	67.33	gold quality
stromal cell of endometrium	CL:0002255	67.31	gold quality
lower esophagus muscularis layer	UBERON:0035833	67.08	gold quality
lower esophagus	UBERON:0013473	67.02	gold quality
cortical plate	UBERON:0005343	66.72	gold quality
corpus callosum	UBERON:0002336	66.40	gold quality
prefrontal cortex	UBERON:0000451	66.16	gold quality
smooth muscle tissue	UBERON:0001135	65.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.