RNFT1-DT
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Summary
RNFT1-DT (RNFT1 divergent transcript, HGNC:51346) is a long non-coding RNA gene on chromosome 17q23.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:51346 |
| Approved symbol | RNFT1-DT |
| Name | RNFT1 divergent transcript |
| Location | 17q23.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000267302 |
| Ensembl biotype | lncRNA |
| Entrez | 101927755 |
| RNAcentral | URS000018F9A0 — lncRNA, 1603 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 2 — 2 lncRNA
ENST00000586209, ENST00000593015
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000586209 — 4 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002739431 | 59995620 | 59996972 |
| ENSE00002877682 | 59965096 | 59965188 |
| ENSE00002920132 | 59992888 | 59992979 |
| ENSE00003626650 | 59966403 | 59966467 |
Expression profiles
Bgee: expression breadth ubiquitous, 133 present calls, max score 81.90.
FANTOM5 (CAGE): breadth broad, TPM avg 1.0575 / max 54.2742, expressed in 549 samples.
FANTOM5 promoters (3 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 162033 | 0.5625 | 330 |
| 162034 | 0.3252 | 157 |
| 162032 | 0.1698 | 78 |
Top tissues by expression
136 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| quadriceps femoris | UBERON:0001377 | 81.90 | gold quality |
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 81.51 | gold quality |
| cerebellar vermis | UBERON:0004720 | 80.21 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 79.00 | gold quality |
| muscle of leg | UBERON:0001383 | 78.95 | gold quality |
| gastrocnemius | UBERON:0001388 | 78.72 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 77.44 | gold quality |
| heart left ventricle | UBERON:0002084 | 74.11 | gold quality |
| right atrium auricular region | UBERON:0006631 | 72.12 | gold quality |
| bone marrow | UBERON:0002371 | 71.99 | gold quality |
| heart | UBERON:0000948 | 71.77 | gold quality |
| apex of heart | UBERON:0002098 | 71.52 | gold quality |
| bone marrow cell | CL:0002092 | 70.09 | silver quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 69.87 | gold quality |
| endometrium | UBERON:0001295 | 69.85 | gold quality |
| stromal cell of endometrium | CL:0002255 | 69.51 | gold quality |
| colonic epithelium | UBERON:0000397 | 68.78 | silver quality |
| subcutaneous adipose tissue | UBERON:0002190 | 68.58 | gold quality |
| liver | UBERON:0002107 | 68.16 | gold quality |
| mucosa of stomach | UBERON:0001199 | 68.15 | gold quality |
| thoracic mammary gland | UBERON:0005200 | 68.15 | gold quality |
| left adrenal gland | UBERON:0001234 | 68.03 | gold quality |
| left adrenal gland cortex | UBERON:0035825 | 67.64 | gold quality |
| testis | UBERON:0000473 | 67.58 | gold quality |
| right adrenal gland cortex | UBERON:0035827 | 67.55 | gold quality |
| right adrenal gland | UBERON:0001233 | 67.39 | gold quality |
| adipose tissue | UBERON:0001013 | 67.33 | gold quality |
| right testis | UBERON:0004534 | 67.27 | gold quality |
| right lobe of liver | UBERON:0001114 | 67.25 | gold quality |
| adrenal gland | UBERON:0002369 | 67.17 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 1.62 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): breast-ovarian cancer, familial, susceptibility to, 2