RNU105B

Summary

RNU105B (RNA, U105B small nucleolar, HGNC:10103) is a small nucleolar RNA gene on chromosome 20p12.3.

Predicted to be involved in RNA processing. Predicted to act upstream of or within response to bacterium. Predicted to be located in nucleolus.

Source: NCBI Gene 26767 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10103
Approved symbol	RNU105B
Name	RNA, U105B small nucleolar
Location	20p12.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	E1-2
Ensembl gene	ENSG00000201348
Ensembl biotype	snoRNA
Entrez	26767
RNAcentral	URS000075C574 — lncRNA, 209 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364478

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364478 — 1 exons

Exon	Start	End
ENSE00001439241	8831186	8831393

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 90.95.

Top tissues by expression

92 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.95	gold quality
cortical plate	UBERON:0005343	84.93	gold quality
skeletal muscle tissue	UBERON:0001134	79.83	gold quality
sural nerve	UBERON:0015488	78.02	gold quality
corpus callosum	UBERON:0002336	77.70	gold quality
bone marrow cell	CL:0002092	73.43	gold quality
tonsil	UBERON:0002372	73.02	gold quality
calcaneal tendon	UBERON:0003701	70.73	gold quality
primary visual cortex	UBERON:0002436	70.28	gold quality
kidney	UBERON:0002113	68.69	gold quality
adult mammalian kidney	UBERON:0000082	68.37	gold quality
bone marrow	UBERON:0002371	68.29	gold quality
monocyte	CL:0000576	68.26	gold quality
prefrontal cortex	UBERON:0000451	64.21	gold quality
stomach	UBERON:0000945	63.99	gold quality
blood	UBERON:0000178	63.94	gold quality
thoracic mammary gland	UBERON:0005200	63.53	gold quality
gastrocnemius	UBERON:0001388	63.34	gold quality
right lobe of liver	UBERON:0001114	62.64	gold quality
uterine cervix	UBERON:0000002	61.69	gold quality
liver	UBERON:0002107	61.23	gold quality
heart left ventricle	UBERON:0002084	60.39	gold quality
body of pancreas	UBERON:0001150	60.03	gold quality
fundus of stomach	UBERON:0001160	59.82	gold quality
heart	UBERON:0000948	59.43	gold quality
tibial artery	UBERON:0007610	59.15	gold quality
adrenal gland	UBERON:0002369	58.80	gold quality
body of stomach	UBERON:0001161	58.54	gold quality
adrenal tissue	UBERON:0018303	58.45	gold quality
small intestine	UBERON:0002108	58.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm25139	ENSMUSG00000065181
mus_musculus	Gm25804	ENSMUSG00000119542
mus_musculus	Gm25483	ENSMUSG00000119770

Paralogs (7): RNU105C (ENSG00000199212), SNORA73 (ENSG00000199977), SNORA73B (ENSG00000200087), SNORA73 (ENSG00000201816), SNORA73 (ENSG00000222145), SNORA73 (ENSG00000253090), SNORA73A (ENSG00000274266)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.