RNU5D-1

Summary

RNU5D-1 (RNA, U5D small nuclear 1, HGNC:10214) is a small nuclear RNA gene on chromosome 1p34.1.

Predicted to be involved in formation of quadruple SL/U4/U5/U6 snRNP and spliceosomal tri-snRNP complex assembly. Predicted to be part of U4/U6 x U5 tri-snRNP complex and U5 snRNP.

Source: NCBI Gene 26830 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10214
Approved symbol	RNU5D-1
Name	RNA, U5D small nuclear 1
Location	1p34.1
Locus type	RNA, small nuclear
Status	Approved
Aliases	U5DS, U5DL
Ensembl gene	ENSG00000200169
Ensembl biotype	snRNA
OMIM	620361
Entrez	26830
RNAcentral	URS00007599E3 — snRNA, 100 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000363299

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000363299 — 1 exons

Exon	Start	End
ENSE00001438062	44731069	44731170

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 98.77.

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	98.77	gold quality
calcaneal tendon	UBERON:0003701	98.75	gold quality
adult mammalian kidney	UBERON:0000082	97.48	gold quality
adrenal tissue	UBERON:0018303	96.78	gold quality
kidney	UBERON:0002113	96.16	gold quality
sural nerve	UBERON:0015488	95.59	gold quality
bone marrow	UBERON:0002371	94.57	gold quality
liver	UBERON:0002107	90.83	gold quality
granulocyte	CL:0000094	90.44	gold quality
monocyte	CL:0000576	89.33	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	85.70	gold quality
stomach	UBERON:0000945	81.29	gold quality
blood	UBERON:0000178	78.85	gold quality
endometrium	UBERON:0001295	77.18	gold quality
skin of abdomen	UBERON:0001416	76.73	gold quality
corpus callosum	UBERON:0002336	76.29	gold quality
lung	UBERON:0002048	75.82	gold quality
islet of Langerhans	UBERON:0000006	75.59	gold quality
adrenal gland	UBERON:0002369	75.17	gold quality
placenta	UBERON:0001987	75.09	gold quality
zone of skin	UBERON:0000014	74.88	gold quality
heart	UBERON:0000948	74.25	gold quality
pancreas	UBERON:0001264	74.02	gold quality
skin of leg	UBERON:0001511	73.12	gold quality
tonsil	UBERON:0002372	73.09	gold quality
fundus of stomach	UBERON:0001160	73.06	gold quality
colon	UBERON:0001155	73.02	gold quality
gastrocnemius	UBERON:0001388	72.84	gold quality
body of pancreas	UBERON:0001150	72.82	gold quality
muscle layer of sigmoid colon	UBERON:0035805	72.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.50

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.