RNVU1-14

Summary

RNVU1-14 (RNA, variant U1 small nuclear 14, HGNC:48319) is a small nuclear RNA gene on chromosome 1q21.2.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 101954266 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48319
Approved symbol	RNVU1-14
Name	RNA, variant U1 small nuclear 14
Location	1q21.2
Locus type	RNA, small nuclear
Status	Approved
Aliases	vU1.14, RNU1-37
Ensembl gene	ENSG00000207501
Ensembl biotype	snRNA
Entrez	101954266
RNAcentral	URS00006C1430 — snRNA, 164 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000384770

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384770 — 1 exons

Exon	Start	End
ENSE00001499778	145281116	145281279

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 97.45.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8680 / max 58.7241, expressed in 422 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
4944	0.8680	422

Top tissues by expression

93 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	97.45	gold quality
sural nerve	UBERON:0015488	96.01	gold quality
liver	UBERON:0002107	85.36	gold quality
calcaneal tendon	UBERON:0003701	79.11	gold quality
adrenal tissue	UBERON:0018303	77.03	gold quality
primary visual cortex	UBERON:0002436	74.66	gold quality
prefrontal cortex	UBERON:0000451	74.34	gold quality
adult mammalian kidney	UBERON:0000082	73.92	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	73.67	gold quality
blood	UBERON:0000178	72.58	gold quality
kidney	UBERON:0002113	71.54	gold quality
lung	UBERON:0002048	71.48	gold quality
lymph node	UBERON:0000029	71.29	gold quality
stomach	UBERON:0000945	71.08	gold quality
right adrenal gland	UBERON:0001233	69.88	gold quality
right lobe of liver	UBERON:0001114	68.77	gold quality
islet of Langerhans	UBERON:0000006	67.51	gold quality
endocervix	UBERON:0000458	67.48	gold quality
monocyte	CL:0000576	65.83	gold quality
fundus of stomach	UBERON:0001160	65.39	gold quality
heart	UBERON:0000948	65.29	gold quality
vermiform appendix	UBERON:0001154	64.82	gold quality
gastrocnemius	UBERON:0001388	64.18	gold quality
intestine	UBERON:0000160	64.10	gold quality
placenta	UBERON:0001987	63.95	gold quality
Brodmann (1909) area 9	UBERON:0013540	63.02	gold quality
heart left ventricle	UBERON:0002084	62.47	gold quality
thoracic mammary gland	UBERON:0005200	62.22	gold quality
putamen	UBERON:0001874	61.29	gold quality
adrenal gland	UBERON:0002369	60.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.