RNVU1-15

Summary

RNVU1-15 (RNA, variant U1 small nuclear 15, HGNC:48320) is a small nuclear RNA gene on chromosome 1q21.2.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 101954267 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48320
Approved symbol	RNVU1-15
Name	RNA, variant U1 small nuclear 15
Location	1q21.2
Locus type	RNA, small nuclear
Status	Approved
Aliases	vU1.15, RNU1-66, vU1.16, RNU1-121
Ensembl gene	ENSG00000207205
Ensembl biotype	snRNA
Entrez	101954267
RNAcentral	URS000069B06F — snRNA, 165 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000384476

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384476 — 1 exons

Exon	Start	End
ENSE00001808588	144412576	144412740

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 96.94.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 24.3179 / max 1015.5965, expressed in 1667 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
201656	24.3179	1667

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.94	gold quality
calcaneal tendon	UBERON:0003701	93.37	gold quality
adrenal tissue	UBERON:0018303	89.35	gold quality
corpus callosum	UBERON:0002336	89.23	gold quality
bone marrow	UBERON:0002371	84.30	gold quality
sural nerve	UBERON:0015488	83.91	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.80	gold quality
liver	UBERON:0002107	82.30	gold quality
monocyte	CL:0000576	80.49	gold quality
granulocyte	CL:0000094	79.92	gold quality
prefrontal cortex	UBERON:0000451	76.10	gold quality
lung	UBERON:0002048	76.10	gold quality
muscle tissue	UBERON:0002385	75.58	gold quality
kidney	UBERON:0002113	74.98	gold quality
blood	UBERON:0000178	74.39	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	73.99	gold quality
stomach	UBERON:0000945	72.78	gold quality
islet of Langerhans	UBERON:0000006	72.73	gold quality
lymph node	UBERON:0000029	70.22	gold quality
adult mammalian kidney	UBERON:0000082	70.05	gold quality
placenta	UBERON:0001987	68.42	gold quality
vermiform appendix	UBERON:0001154	67.98	gold quality
heart	UBERON:0000948	67.70	gold quality
gastrocnemius	UBERON:0001388	67.16	gold quality
adrenal gland	UBERON:0002369	66.63	gold quality
smooth muscle tissue	UBERON:0001135	66.28	gold quality
tibial artery	UBERON:0007610	65.42	gold quality
right lobe of liver	UBERON:0001114	65.24	gold quality
body of pancreas	UBERON:0001150	65.07	gold quality
right ovary	UBERON:0002118	64.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.