RNVU1-19

Summary

RNVU1-19 (RNA, variant U1 small nuclear 19, HGNC:48324) is a small nuclear RNA gene on chromosome 1q21.2.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 101954277 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48324
Approved symbol	RNVU1-19
Name	RNA, variant U1 small nuclear 19
Location	1q21.2
Locus type	RNA, small nuclear
Status	Approved
Aliases	vU1.19, RNU1-126, vU1.13, RNU1-147
Ensembl gene	ENSG00000275538
Ensembl biotype	snRNA
Entrez	101954277
RNAcentral	URS000075AD80 — snRNA, 167 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000613023

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000613023 — 1 exons

Exon	Start	End
ENSE00003719321	120850819	120850985

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 92.72.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 23.0081 / max 1051.0316, expressed in 1534 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
14108	23.0081	1534

Top tissues by expression

92 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	92.72	gold quality
cortical plate	UBERON:0005343	91.52	gold quality
liver	UBERON:0002107	81.93	gold quality
adult mammalian kidney	UBERON:0000082	80.35	gold quality
adrenal tissue	UBERON:0018303	78.03	gold quality
lymph node	UBERON:0000029	76.63	gold quality
calcaneal tendon	UBERON:0003701	74.26	gold quality
primary visual cortex	UBERON:0002436	72.81	gold quality
kidney	UBERON:0002113	72.73	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.48	gold quality
muscle of leg	UBERON:0001383	69.77	gold quality
lung	UBERON:0002048	69.50	gold quality
stomach	UBERON:0000945	69.25	gold quality
monocyte	CL:0000576	67.83	gold quality
islet of Langerhans	UBERON:0000006	67.32	gold quality
blood	UBERON:0000178	66.89	gold quality
heart	UBERON:0000948	66.71	gold quality
bone marrow	UBERON:0002371	66.18	gold quality
adrenal gland	UBERON:0002369	65.67	gold quality
gastrocnemius	UBERON:0001388	65.39	gold quality
right ovary	UBERON:0002118	64.98	gold quality
descending thoracic aorta	UBERON:0002345	64.47	gold quality
body of pancreas	UBERON:0001150	61.76	gold quality
vermiform appendix	UBERON:0001154	61.43	gold quality
heart left ventricle	UBERON:0002084	61.25	gold quality
tibial artery	UBERON:0007610	61.06	gold quality
left coronary artery	UBERON:0001626	60.96	gold quality
lower esophagus muscularis layer	UBERON:0035833	59.80	gold quality
thoracic aorta	UBERON:0001515	59.66	gold quality
prostate gland	UBERON:0002367	59.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.