RNVU1-24

Summary

RNVU1-24 (RNA, variant U1 small nuclear 24, HGNC:48401) is a small nuclear RNA gene on chromosome 1q21.1.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 106480167 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48401
Approved symbol	RNVU1-24
Name	RNA, variant U1 small nuclear 24
Location	1q21.1
Locus type	RNA, small nuclear
Status	Approved
Ensembl gene	ENSG00000201699
Ensembl biotype	snRNA
Entrez	106480167
RNAcentral	URS0000C0EBCC — snRNA, 162 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000364829

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364829 — 1 exons

Exon	Start	End
ENSE00001439592	149162783	149162944

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 95.67.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4267 / max 28.9294, expressed in 205 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
201704	0.4267	205

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	95.67	gold quality
sural nerve	UBERON:0015488	92.06	gold quality
calcaneal tendon	UBERON:0003701	78.58	gold quality
muscle tissue	UBERON:0002385	76.83	gold quality
primary visual cortex	UBERON:0002436	76.54	gold quality
monocyte	CL:0000576	72.75	gold quality
prefrontal cortex	UBERON:0000451	71.52	gold quality
apex of heart	UBERON:0002098	71.15	gold quality
muscle of leg	UBERON:0001383	70.49	gold quality
gastrocnemius	UBERON:0001388	69.94	gold quality
bone marrow	UBERON:0002371	69.21	gold quality
skeletal muscle tissue	UBERON:0001134	66.32	gold quality
urinary bladder	UBERON:0001255	66.23	gold quality
blood	UBERON:0000178	66.00	gold quality
cerebellum	UBERON:0002037	65.92	gold quality
cerebellar cortex	UBERON:0002129	65.81	gold quality
cerebellar hemisphere	UBERON:0002245	65.80	gold quality
right adrenal gland	UBERON:0001233	65.59	gold quality
heart left ventricle	UBERON:0002084	65.57	gold quality
right hemisphere of cerebellum	UBERON:0014890	65.45	gold quality
islet of Langerhans	UBERON:0000006	65.44	gold quality
liver	UBERON:0002107	65.44	gold quality
Brodmann (1909) area 9	UBERON:0013540	65.32	gold quality
corpus callosum	UBERON:0002336	64.79	gold quality
heart	UBERON:0000948	63.92	gold quality
substantia nigra	UBERON:0002038	63.79	gold quality
lymph node	UBERON:0000029	63.51	gold quality
rectum	UBERON:0001052	63.09	gold quality
nucleus accumbens	UBERON:0001882	62.95	gold quality
brain	UBERON:0000955	61.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.41

Regulation

Is transcription factor: no

Cross-species orthologs

1 orthologs

Organism	Symbol	Gene ID
danio_rerio	U1	ENSDARG00000084068

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.