RNVU1-26

Summary

RNVU1-26 (RNA, variant U1 small nuclear 26, HGNC:54429) is a small nuclear RNA gene on chromosome 1q21.1.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 124904624 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54429
Approved symbol	RNVU1-26
Name	RNA, variant U1 small nuclear 26
Location	1q21.1
Locus type	RNA, small nuclear
Status	Approved
Ensembl gene	ENSG00000275291
Ensembl biotype	snRNA
Entrez	124904624
RNAcentral	URS0000648A89 — snRNA, 162 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000618578

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000618578 — 1 exons

Exon	Start	End
ENSE00003712175	144523860	144524021

Expression profiles

Bgee: expression breadth broad, 94 present calls, max score 95.87.

Top tissues by expression

94 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.87	gold quality
granulocyte	CL:0000094	84.90	gold quality
calcaneal tendon	UBERON:0003701	79.52	gold quality
muscle tissue	UBERON:0002385	76.83	gold quality
adrenal tissue	UBERON:0018303	75.69	gold quality
bone marrow	UBERON:0002371	74.90	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	73.42	gold quality
monocyte	CL:0000576	71.11	gold quality
muscle of leg	UBERON:0001383	67.12	gold quality
blood	UBERON:0000178	67.03	gold quality
skeletal muscle tissue	UBERON:0001134	66.32	gold quality
liver	UBERON:0002107	65.83	gold quality
islet of Langerhans	UBERON:0000006	65.63	gold quality
adrenal gland	UBERON:0002369	65.59	gold quality
corpus callosum	UBERON:0002336	64.79	gold quality
gastrocnemius	UBERON:0001388	64.23	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.17	gold quality
cerebellar cortex	UBERON:0002129	63.41	gold quality
cerebellar hemisphere	UBERON:0002245	63.36	gold quality
rectum	UBERON:0001052	63.09	gold quality
nucleus accumbens	UBERON:0001882	62.84	gold quality
prefrontal cortex	UBERON:0000451	62.38	gold quality
lymph node	UBERON:0000029	61.69	gold quality
substantia nigra	UBERON:0002038	61.48	gold quality
myometrium	UBERON:0001296	61.47	gold quality
placenta	UBERON:0001987	61.45	gold quality
transverse colon	UBERON:0001157	60.87	gold quality
right hemisphere of cerebellum	UBERON:0014890	60.68	gold quality
heart left ventricle	UBERON:0002084	60.56	gold quality
right lobe of liver	UBERON:0001114	60.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.95

Regulation

Is transcription factor: no

Cross-species orthologs

1 orthologs

Organism	Symbol	Gene ID
danio_rerio	U1	ENSDARG00000084068

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.