RNVU1-3

Summary

RNVU1-3 (RNA, variant U1 small nuclear 3, HGNC:48311) is a small nuclear RNA gene on chromosome 1q21.1.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 101954272 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48311
Approved symbol	RNVU1-3
Name	RNA, variant U1 small nuclear 3
Location	1q21.1
Locus type	RNA, small nuclear
Status	Approved
Aliases	vU1.3, RNU1-113, vU1.12, RNU1-151
Ensembl gene	ENSG00000201183
Ensembl biotype	snRNA
Entrez	101954272
RNAcentral	URS000075CD30 — snRNA, 161 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000364313

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364313 — 1 exons

Exon	Start	End
ENSE00001808668	148402715	148402875

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 92.52.

FANTOM5 (CAGE): breadth broad, TPM avg 1.9528 / max 104.2428, expressed in 490 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
201698	1.9528	490

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
superior frontal gyrus	UBERON:0002661	92.52	gold quality
monocyte	CL:0000576	85.39	gold quality
bone marrow	UBERON:0002371	81.07	gold quality
sural nerve	UBERON:0015488	80.46	gold quality
prefrontal cortex	UBERON:0000451	79.07	gold quality
primary visual cortex	UBERON:0002436	78.52	gold quality
right uterine tube	UBERON:0001302	77.25	gold quality
blood	UBERON:0000178	76.59	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	76.57	gold quality
calcaneal tendon	UBERON:0003701	76.01	gold quality
endocervix	UBERON:0000458	74.93	gold quality
adenohypophysis	UBERON:0002196	74.92	gold quality
Brodmann (1909) area 9	UBERON:0013540	74.82	gold quality
skeletal muscle tissue	UBERON:0001134	73.98	gold quality
pituitary gland	UBERON:0000007	73.75	gold quality
ectocervix	UBERON:0012249	73.51	gold quality
cerebellar cortex	UBERON:0002129	73.41	gold quality
cerebellum	UBERON:0002037	73.37	gold quality
cerebellar hemisphere	UBERON:0002245	73.26	gold quality
adrenal tissue	UBERON:0018303	72.91	gold quality
right hemisphere of cerebellum	UBERON:0014890	72.47	gold quality
corpus callosum	UBERON:0002336	72.20	gold quality
islet of Langerhans	UBERON:0000006	72.16	gold quality
endometrium	UBERON:0001295	71.98	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	71.86	gold quality
urinary bladder	UBERON:0001255	71.00	gold quality
right lung	UBERON:0002167	70.84	gold quality
left uterine tube	UBERON:0001303	70.74	gold quality
right ovary	UBERON:0002118	70.66	gold quality
lymph node	UBERON:0000029	70.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.