RNVU1-30

Summary

RNVU1-30 (RNA, variant U1 small nuclear 30, HGNC:54434) is a small nuclear RNA gene on chromosome 1q21.2.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 124904627 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54434
Approved symbol	RNVU1-30
Name	RNA, variant U1 small nuclear 30
Location	1q21.2
Locus type	RNA, small nuclear
Status	Approved
Ensembl gene	ENSG00000206828
Ensembl biotype	snRNA
Entrez	124904627
RNAcentral	URS0002853ABA — snRNA, 254 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000384101

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384101 — 1 exons

Exon	Start	End
ENSE00001807019	149636766	149636929

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 96.51.

FANTOM5 (CAGE): breadth broad, TPM avg 3.1889 / max 1363.7040, expressed in 623 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
5026	3.1889	623

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	96.51	gold quality
leukocyte	CL:0000738	95.96	gold quality
bone marrow	UBERON:0002371	91.75	gold quality
granulocyte	CL:0000094	90.53	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.90	gold quality
adrenal tissue	UBERON:0018303	83.60	gold quality
sural nerve	UBERON:0015488	83.37	gold quality
calcaneal tendon	UBERON:0003701	83.22	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	80.33	gold quality
left uterine tube	UBERON:0001303	78.71	gold quality
blood	UBERON:0000178	77.72	gold quality
liver	UBERON:0002107	76.87	gold quality
pituitary gland	UBERON:0000007	76.37	gold quality
prefrontal cortex	UBERON:0000451	76.29	gold quality
islet of Langerhans	UBERON:0000006	76.16	gold quality
right lobe of liver	UBERON:0001114	75.99	gold quality
adenohypophysis	UBERON:0002196	75.80	gold quality
vermiform appendix	UBERON:0001154	75.56	gold quality
primary visual cortex	UBERON:0002436	75.22	gold quality
mucosa of transverse colon	UBERON:0004991	75.00	gold quality
lung	UBERON:0002048	73.03	gold quality
endometrium	UBERON:0001295	72.55	gold quality
fallopian tube	UBERON:0003889	72.54	gold quality
small intestine	UBERON:0002108	72.50	gold quality
small intestine Peyer’s patch	UBERON:0003454	72.41	gold quality
transverse colon	UBERON:0001157	72.37	gold quality
stomach	UBERON:0000945	72.26	gold quality
intestine	UBERON:0000160	72.23	gold quality
omental fat pad	UBERON:0010414	72.18	gold quality
body of pancreas	UBERON:0001150	72.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.21

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.