RNVU1-32

Summary

RNVU1-32 (RNA, variant U1 small nuclear 32, HGNC:48448) is a small nuclear RNA gene on chromosome 8q24.21.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 106481624 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48448
Approved symbol	RNVU1-32
Name	RNA, variant U1 small nuclear 32
Location	8q24.21
Locus type	RNA, small nuclear
Status	Approved
Aliases	U1A4
Ensembl gene	ENSG00000207110
Ensembl biotype	snRNA
Entrez	106481624
RNAcentral	URS0000705A6A — snRNA, 164 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000384382

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384382 — 1 exons

Exon	Start	End
ENSE00001807188	127999131	127999294

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 87.29.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4369 / max 31.3612, expressed in 201 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
205328	0.4369	201

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.29	silver quality
sural nerve	UBERON:0015488	82.19	gold quality
liver	UBERON:0002107	72.95	gold quality
monocyte	CL:0000576	72.60	gold quality
bone marrow	UBERON:0002371	70.46	gold quality
mucosa of transverse colon	UBERON:0004991	70.35	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.38	gold quality
blood	UBERON:0000178	69.20	gold quality
prefrontal cortex	UBERON:0000451	68.51	gold quality
granulocyte	CL:0000094	68.05	gold quality
adrenal tissue	UBERON:0018303	67.95	gold quality
myometrium	UBERON:0001296	67.85	gold quality
metanephros cortex	UBERON:0010533	67.41	gold quality
islet of Langerhans	UBERON:0000006	67.28	gold quality
urinary bladder	UBERON:0001255	66.50	gold quality
adult mammalian kidney	UBERON:0000082	66.32	gold quality
kidney	UBERON:0002113	65.68	gold quality
lymph node	UBERON:0000029	65.48	gold quality
left ovary	UBERON:0002119	64.59	gold quality
vermiform appendix	UBERON:0001154	64.24	gold quality
muscle of leg	UBERON:0001383	63.79	gold quality
gastrocnemius	UBERON:0001388	63.77	gold quality
tonsil	UBERON:0002372	63.64	gold quality
endometrium	UBERON:0001295	63.33	gold quality
ovary	UBERON:0000992	63.14	gold quality
placenta	UBERON:0001987	63.10	gold quality
lung	UBERON:0002048	62.25	gold quality
calcaneal tendon	UBERON:0003701	62.14	gold quality
right lobe of liver	UBERON:0001114	61.88	gold quality
stomach	UBERON:0000945	61.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.81

Regulation

Is transcription factor: no

Cross-species orthologs

1 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm23330	ENSMUSG00000119106

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.