RNVU1-7

Summary

RNVU1-7 (RNA, variant U1 small nuclear 7, HGNC:37500) is a small nuclear RNA gene on chromosome 1q21.1.

Predicted to enable pre-mRNA 5’-splice site binding activity. Predicted to be involved in mRNA 5’-splice site recognition. Predicted to be part of U1 snRNP.

Source: NCBI Gene 26864 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37500
Approved symbol	RNVU1-7
Name	RNA, variant U1 small nuclear 7
Location	1q21.1
Locus type	RNA, small nuclear
Status	Approved
Aliases	vU1.7, vU1.9
Ensembl gene	ENSG00000206585
Ensembl biotype	snRNA
Entrez	26864
RNAcentral	URS00000081EA — snRNA, 164 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snRNA

ENST00000383858

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000383858 — 1 exons

Exon	Start	End
ENSE00001809139	148038753	148038916

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 99.91.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1829 / max 15.8044, expressed in 85 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
10541	0.1829	85

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	99.91	gold quality
sural nerve	UBERON:0015488	99.89	gold quality
corpus callosum	UBERON:0002336	99.88	gold quality
calcaneal tendon	UBERON:0003701	95.76	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.57	gold quality
blood	UBERON:0000178	90.05	gold quality
monocyte	CL:0000576	86.53	gold quality
metanephros cortex	UBERON:0010533	85.84	gold quality
liver	UBERON:0002107	85.42	gold quality
cerebellar hemisphere	UBERON:0002245	84.68	gold quality
skeletal muscle tissue	UBERON:0001134	83.27	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.13	gold quality
hypothalamus	UBERON:0001898	82.63	gold quality
amygdala	UBERON:0001876	81.68	gold quality
lung	UBERON:0002048	81.42	gold quality
right frontal lobe	UBERON:0002810	81.23	gold quality
brain	UBERON:0000955	80.74	gold quality
anterior cingulate cortex	UBERON:0009835	80.52	gold quality
substantia nigra	UBERON:0002038	79.98	gold quality
kidney	UBERON:0002113	79.94	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.89	gold quality
right lung	UBERON:0002167	79.79	gold quality
nucleus accumbens	UBERON:0001882	79.47	gold quality
putamen	UBERON:0001874	79.39	gold quality
pituitary gland	UBERON:0000007	79.04	gold quality
cortex of kidney	UBERON:0001225	79.04	gold quality
Ammon’s horn	UBERON:0001954	78.98	gold quality
frontal cortex	UBERON:0001870	78.81	gold quality
thoracic mammary gland	UBERON:0005200	78.63	gold quality
caudate nucleus	UBERON:0001873	78.61	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (147): RNU1-75P (ENSG00000194297), RNU1-15P (ENSG00000195024), RNU1-58P (ENSG00000199283), RNU1-150P (ENSG00000199361), RNU1-108P (ENSG00000199426), RNU1-62P (ENSG00000199469), RNU1-70P (ENSG00000199488), RNU1-94P (ENSG00000199497), RNU1-14P (ENSG00000199629), RNU1-35P (ENSG00000199652), RNU1-38P (ENSG00000199687), RNU1-76P (ENSG00000199773), RNU1-134P (ENSG00000199805), RNU1-47P (ENSG00000199836), RNU1-72P (ENSG00000199846), RNVU1-22 (ENSG00000199879), RNU1-17P (ENSG00000199892), RNU1-18P (ENSG00000199932), RNU1-19P (ENSG00000200176), RNU1-20P (ENSG00000200184), RNU1-21P (ENSG00000200197), RNU1-22P (ENSG00000200204), RNU1-23P (ENSG00000200231), RNU1-83P (ENSG00000200296), RNU1-49P (ENSG00000200338), RNU1-105P (ENSG00000200340), RNVU1-33 (ENSG00000200597), RNU1-124P (ENSG00000200731), RNU1-31P (ENSG00000200745), RNU1-65P (ENSG00000200789), RNU1-130P (ENSG00000200800), RNU1-32P (ENSG00000200807), RNU1-146P (ENSG00000200885), RNU1-42P (ENSG00000200903), RNU1-7P (ENSG00000200975), RNVU1-34 (ENSG00000200997), RNU1-96P (ENSG00000201033), RNU1-33P (ENSG00000201119), RNU1-151P (ENSG00000201142), RNU1-24P (ENSG00000201155)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.