ROPN1L-AS1

Summary

ROPN1L-AS1 (ROPN1L antisense RNA 1, HGNC:39984) is a long non-coding RNA gene on chromosome 5p15.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39984
Approved symbol	ROPN1L-AS1
Name	ROPN1L antisense RNA 1
Location	5p15.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250600
Ensembl biotype	lncRNA
Entrez	100505845
RNAcentral	URS000075E3F1 — lncRNA, 803 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000513037, ENST00000702123, ENST00000785192

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000513037 — 3 exons

Exon	Start	End
ENSE00004160776	10440888	10441373
ENSE00004160779	10441688	10441936
ENSE00004160780	10435098	10435365

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 92.53.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0765 / max 12.5491, expressed in 17 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
60897	0.0765	17

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.53	gold quality
left testis	UBERON:0004533	87.92	gold quality
testis	UBERON:0000473	87.26	gold quality
right testis	UBERON:0004534	86.61	gold quality
monocyte	CL:0000576	71.43	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	70.95	gold quality
islet of Langerhans	UBERON:0000006	69.00	gold quality
fallopian tube	UBERON:0003889	65.55	gold quality
blood	UBERON:0000178	65.43	gold quality
heart left ventricle	UBERON:0002084	63.73	gold quality
gastrocnemius	UBERON:0001388	63.38	gold quality
left coronary artery	UBERON:0001626	63.24	gold quality
calcaneal tendon	UBERON:0003701	62.86	gold quality
adrenal tissue	UBERON:0018303	62.45	gold quality
tibial artery	UBERON:0007610	61.94	gold quality
lymph node	UBERON:0000029	61.76	gold quality
heart	UBERON:0000948	59.95	gold quality
body of pancreas	UBERON:0001150	59.84	gold quality
ovary	UBERON:0000992	59.76	gold quality
Brodmann (1909) area 9	UBERON:0013540	59.49	gold quality
right ovary	UBERON:0002118	59.47	gold quality
esophagus mucosa	UBERON:0002469	59.43	gold quality
esophagus	UBERON:0001043	59.34	gold quality
thoracic aorta	UBERON:0001515	59.33	gold quality
liver	UBERON:0002107	59.29	gold quality
lower esophagus muscularis layer	UBERON:0035833	59.24	gold quality
lower esophagus	UBERON:0013473	59.09	gold quality
body of stomach	UBERON:0001161	59.07	gold quality
ascending aorta	UBERON:0001496	58.97	gold quality
stomach	UBERON:0000945	58.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.