RORA-AS1

Summary

RORA-AS1 (RORA antisense RNA 1, HGNC:51410) is a long non-coding RNA gene on chromosome 15q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51410
Approved symbol	RORA-AS1
Name	RORA antisense RNA 1
Location	15q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245534
Ensembl biotype	lncRNA
Entrez	101928784
RNAcentral	URS000075E4CB — lncRNA, 1949 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000501579, ENST00000558140, ENST00000558235, ENST00000559203, ENST00000559824, ENST00000559902, ENST00000560280, ENST00000660694, ENST00000841380, ENST00000841381, ENST00000841382, ENST00000841383, ENST00000841384

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501579 — 6 exons

Exon	Start	End
ENSE00001959920	60510408	60510533
ENSE00001963260	60519966	60520269
ENSE00001981352	60488524	60488591
ENSE00001983846	60528580	60528727
ENSE00003858328	60479152	60479398
ENSE00003880738	60544374	60544452

Expression profiles

Bgee: expression breadth ubiquitous, 163 present calls, max score 87.22.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.8011 / max 58.4314, expressed in 992 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
147024	2.7505	987
147023	0.0505	15

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.22	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.61	gold quality
adrenal tissue	UBERON:0018303	80.95	gold quality
bone marrow cell	CL:0002092	80.11	gold quality
colonic epithelium	UBERON:0000397	79.56	gold quality
buccal mucosa cell	CL:0002336	76.99	silver quality
secondary oocyte	CL:0000655	76.58	gold quality
calcaneal tendon	UBERON:0003701	75.11	gold quality
right testis	UBERON:0004534	74.94	gold quality
testis	UBERON:0000473	74.90	gold quality
left testis	UBERON:0004533	74.78	gold quality
right uterine tube	UBERON:0001302	70.83	gold quality
skin of abdomen	UBERON:0001416	69.71	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	69.58	gold quality
oviduct epithelium	UBERON:0004804	69.45	gold quality
cortical plate	UBERON:0005343	69.11	gold quality
sperm	CL:0000019	68.11	silver quality
islet of Langerhans	UBERON:0000006	68.10	gold quality
sural nerve	UBERON:0015488	68.00	gold quality
oocyte	CL:0000023	67.84	gold quality
tendon	UBERON:0000043	67.60	gold quality
upper arm skin	UBERON:0004263	66.71	gold quality
lymph node	UBERON:0000029	66.43	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.42	gold quality
skin of leg	UBERON:0001511	66.41	gold quality
zone of skin	UBERON:0000014	65.71	gold quality
corpus callosum	UBERON:0002336	65.59	gold quality
stromal cell of endometrium	CL:0002255	65.37	gold quality
leukocyte	CL:0000738	65.28	gold quality
ventricular zone	UBERON:0003053	65.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.83

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.