RORA-AS4

Summary

RORA-AS4 (RORA antisense RNA 4, HGNC:58471) is a long non-coding RNA gene on chromosome 15q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58471
Approved symbol	RORA-AS4
Name	RORA antisense RNA 4
Location	15q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259591
Ensembl biotype	lncRNA
Entrez	105370844

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000558630, ENST00000560864, ENST00000671250

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000558630 — 2 exons

Exon	Start	End
ENSE00002562353	60763906	60764081
ENSE00002564033	60764742	60765035

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 93.10.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	93.10	gold quality
left testis	UBERON:0004533	75.18	gold quality
testis	UBERON:0000473	75.08	gold quality
right testis	UBERON:0004534	74.64	gold quality
skeletal muscle tissue	UBERON:0001134	73.55	gold quality
bone marrow	UBERON:0002371	71.81	silver quality
colonic epithelium	UBERON:0000397	71.64	gold quality
calcaneal tendon	UBERON:0003701	68.37	gold quality
thymus	UBERON:0002370	66.96	silver quality
hindlimb stylopod muscle	UBERON:0004252	64.98	gold quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
duodenum	UBERON:0002114	62.36	gold quality
tonsil	UBERON:0002372	62.13	silver quality
liver	UBERON:0002107	61.00	gold quality
corpus callosum	UBERON:0002336	57.82	gold quality
adrenal tissue	UBERON:0018303	56.01	gold quality
muscle of leg	UBERON:0001383	55.74	gold quality
urinary bladder	UBERON:0001255	54.99	gold quality
blood	UBERON:0000178	54.44	gold quality
superior frontal gyrus	UBERON:0002661	53.06	gold quality
lower esophagus mucosa	UBERON:0035834	53.00	gold quality
cerebellum	UBERON:0002037	52.74	gold quality
cerebellar cortex	UBERON:0002129	52.48	gold quality
kidney	UBERON:0002113	52.47	gold quality
monocyte	CL:0000576	52.43	gold quality
right lobe of liver	UBERON:0001114	52.41	gold quality
endometrium	UBERON:0001295	52.31	gold quality
primary visual cortex	UBERON:0002436	52.22	gold quality
cerebellar hemisphere	UBERON:0002245	52.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.