RPP38-DT

Summary

RPP38-DT (RPP38 divergent transcript, HGNC:28582) is a long non-coding RNA gene on chromosome 10p13.

Predicted to be located in membrane.

Source: NCBI Gene 221060 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28582
Approved symbol	RPP38-DT
Name	RPP38 divergent transcript
Location	10p13
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC35468, bA455B2.4
Ensembl gene	ENSG00000176236
Ensembl biotype	lncRNA
Entrez	221060
RNAcentral	URS00007DCF59 — lncRNA, 1714 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000624760

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000624760 — 2 exons

Exon	Start	End
ENSE00001287615	15097087	15097319
ENSE00001476647	15095385	15096865

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 80.49.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6395 / max 70.6834, expressed in 148 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
108410	0.6395	148

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.49	gold quality
right uterine tube	UBERON:0001302	76.57	gold quality
cortical plate	UBERON:0005343	66.77	gold quality
ventricular zone	UBERON:0003053	66.26	gold quality
bone marrow cell	CL:0002092	65.26	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	63.91	gold quality
ganglionic eminence	UBERON:0004023	60.67	gold quality
testis	UBERON:0000473	60.62	gold quality
body of pancreas	UBERON:0001150	60.56	gold quality
right testis	UBERON:0004534	60.29	gold quality
left testis	UBERON:0004533	60.01	gold quality
skeletal muscle tissue	UBERON:0001134	59.66	gold quality
bone marrow	UBERON:0002371	59.39	gold quality
nucleus accumbens	UBERON:0001882	59.22	gold quality
prefrontal cortex	UBERON:0000451	59.20	gold quality
caudate nucleus	UBERON:0001873	57.81	gold quality
pancreas	UBERON:0001264	57.67	gold quality
cerebellum	UBERON:0002037	57.57	gold quality
cerebellar cortex	UBERON:0002129	57.50	gold quality
cerebellar hemisphere	UBERON:0002245	57.44	gold quality
primary visual cortex	UBERON:0002436	57.10	gold quality
frontal cortex	UBERON:0001870	57.09	gold quality
superior frontal gyrus	UBERON:0002661	56.80	gold quality
fallopian tube	UBERON:0003889	56.70	gold quality
hypothalamus	UBERON:0001898	56.55	gold quality
cerebral cortex	UBERON:0000956	56.41	gold quality
stromal cell of endometrium	CL:0002255	56.37	gold quality
brain	UBERON:0000955	56.28	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	56.22	gold quality
right hemisphere of cerebellum	UBERON:0014890	56.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.