RPS6KA2-IT1

Summary

RPS6KA2-IT1 (RPS6KA2 intronic transcript 1, HGNC:41378) is a long non-coding RNA gene on chromosome 6q27.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41378
Approved symbol	RPS6KA2-IT1
Name	RPS6KA2 intronic transcript 1
Location	6q27
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232082
Ensembl biotype	lncRNA
Entrez	100874353
RNAcentral	URS000018AE61 — lncRNA, 579 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000416770

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416770 — 4 exons

Exon	Start	End
ENSE00001611333	166465325	166465383
ENSE00001659043	166462986	166463141
ENSE00001751114	166463320	166463507
ENSE00001771977	166460663	166460838

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 68.27.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	68.27	gold quality
bone marrow cell	CL:0002092	66.94	silver quality
apex of heart	UBERON:0002098	66.77	gold quality
sural nerve	UBERON:0015488	65.85	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.35	gold quality
heart left ventricle	UBERON:0002084	64.92	gold quality
ganglionic eminence	UBERON:0004023	62.56	gold quality
upper lobe of left lung	UBERON:0008952	62.25	gold quality
skeletal muscle tissue	UBERON:0001134	62.10	gold quality
cortical plate	UBERON:0005343	61.82	gold quality
bone marrow	UBERON:0002371	61.49	gold quality
lung	UBERON:0002048	61.03	gold quality
heart	UBERON:0000948	60.20	gold quality
right lung	UBERON:0002167	60.12	gold quality
subcutaneous adipose tissue	UBERON:0002190	59.89	gold quality
lower esophagus mucosa	UBERON:0035834	59.36	gold quality
muscle of leg	UBERON:0001383	59.08	gold quality
calcaneal tendon	UBERON:0003701	59.05	gold quality
gastrocnemius	UBERON:0001388	58.70	gold quality
gall bladder	UBERON:0002110	58.09	gold quality
prefrontal cortex	UBERON:0000451	57.81	gold quality
right atrium auricular region	UBERON:0006631	57.32	gold quality
adipose tissue	UBERON:0001013	56.77	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	55.95	gold quality
islet of Langerhans	UBERON:0000006	55.39	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.22	gold quality
frontal cortex	UBERON:0001870	55.20	gold quality
Brodmann (1909) area 9	UBERON:0013540	53.82	gold quality
myometrium	UBERON:0001296	53.62	gold quality
cerebral cortex	UBERON:0000956	53.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.