RPS6KB2-AS1

Summary

RPS6KB2-AS1 (RPS6KB2 antisense RNA 1, HGNC:53744) is a long non-coding RNA gene on chromosome 11q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53744
Approved symbol	RPS6KB2-AS1
Name	RPS6KB2 antisense RNA 1
Location	11q13.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AP003419.16
Ensembl gene	ENSG00000255949
Ensembl biotype	lncRNA
Entrez	111216279
RNAcentral	URS00005BC91E — lncRNA, 470 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000535922

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000535922 — 2 exons

Exon	Start	End
ENSE00002214608	67431367	67431493
ENSE00002230833	67435057	67435399

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 87.55.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0305 / max 7.5655, expressed in 14 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
120921	0.0305	14

Top tissues by expression

89 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.55	gold quality
blood	UBERON:0000178	80.93	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.31	gold quality
hindlimb stylopod muscle	UBERON:0004252	79.84	gold quality
kidney	UBERON:0002113	74.55	gold quality
primary visual cortex	UBERON:0002436	74.48	gold quality
urinary bladder	UBERON:0001255	74.12	gold quality
liver	UBERON:0002107	74.04	gold quality
cortical plate	UBERON:0005343	73.72	gold quality
anterior cingulate cortex	UBERON:0009835	73.25	gold quality
small intestine	UBERON:0002108	73.17	gold quality
skeletal muscle tissue	UBERON:0001134	73.05	gold quality
lymph node	UBERON:0000029	73.03	gold quality
sural nerve	UBERON:0015488	72.56	gold quality
tonsil	UBERON:0002372	72.51	gold quality
bone marrow cell	CL:0002092	72.20	gold quality
adult mammalian kidney	UBERON:0000082	71.79	gold quality
cortex of kidney	UBERON:0001225	71.63	gold quality
colonic epithelium	UBERON:0000397	70.96	gold quality
myometrium	UBERON:0001296	70.38	silver quality
ganglionic eminence	UBERON:0004023	69.68	gold quality
temporal lobe	UBERON:0001871	68.39	gold quality
uterine cervix	UBERON:0000002	66.08	silver quality
superior frontal gyrus	UBERON:0002661	65.93	gold quality
pancreas	UBERON:0001264	63.29	gold quality
cerebellum	UBERON:0002037	63.21	gold quality
ovary	UBERON:0000992	62.44	gold quality
prefrontal cortex	UBERON:0000451	59.69	gold quality
cerebellar cortex	UBERON:0002129	59.12	gold quality
frontal cortex	UBERON:0001870	59.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.