RRS1-DT

Summary

RRS1-DT (RRS1 divergent transcript, HGNC:50465) is a long non-coding RNA gene on chromosome 8q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50465
Approved symbol	RRS1-DT
Name	RRS1 divergent transcript
Location	8q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246145
Ensembl biotype	lncRNA
Entrez	100505676
RNAcentral	URS000075AA92 — lncRNA, 4372 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 33 — 33 lncRNA

ENST00000499642, ENST00000659008, ENST00000734543, ENST00000734544, ENST00000734545, ENST00000734546, ENST00000734547, ENST00000734548, ENST00000734549, ENST00000734550, ENST00000734551, ENST00000734552, ENST00000734553, ENST00000734554, ENST00000734555, ENST00000734556, ENST00000734557, ENST00000734558, ENST00000734559, ENST00000734560, ENST00000734561, ENST00000734562, ENST00000734563, ENST00000734564, ENST00000734565, ENST00000734566, ENST00000734567, ENST00000734568, ENST00000734569, ENST00000734570, ENST00000734834, ENST00000734835, ENST00000734836

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499642 — 3 exons

Exon	Start	End
ENSE00001963053	66426042	66426177
ENSE00004067196	66419589	66423782
ENSE00004067211	66428942	66428984

Expression profiles

Bgee: expression breadth broad, 39 present calls, max score 47.36.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0327 / max 10.3750, expressed in 11 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
93401	0.0327	11

Top tissues by expression

159 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	47.36	silver quality
liver	UBERON:0002107	47.25	silver quality
islet of Langerhans	UBERON:0000006	47.23	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	46.84	silver quality
cortex of kidney	UBERON:0001225	46.80	gold quality
descending thoracic aorta	UBERON:0002345	46.68	gold quality
tendon of biceps brachii	UBERON:0008188	45.43	gold quality
lymph node	UBERON:0000029	45.19	silver quality
stomach	UBERON:0000945	45.01	gold quality
pancreas	UBERON:0001264	45.00	silver quality
body of stomach	UBERON:0001161	44.94	silver quality
right lobe of liver	UBERON:0001114	44.85	silver quality
adult mammalian kidney	UBERON:0000082	44.84	silver quality
kidney	UBERON:0002113	44.29	silver quality
gastrocnemius	UBERON:0001388	44.12	silver quality
tibial artery	UBERON:0007610	43.43	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
tonsil	UBERON:0002372	43.28	gold quality
oviduct epithelium	UBERON:0004804	42.80	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
aorta	UBERON:0000947	42.43	silver quality
body of pancreas	UBERON:0001150	42.34	silver quality
blood	UBERON:0000178	42.04	gold quality
prefrontal cortex	UBERON:0000451	41.79	gold quality
fallopian tube	UBERON:0003889	41.78	gold quality
prostate gland	UBERON:0002367	41.75	silver quality
skeletal muscle tissue	UBERON:0001134	41.65	gold quality
left coronary artery	UBERON:0001626	41.65	silver quality
fundus of stomach	UBERON:0001160	41.59	silver quality
vastus lateralis	UBERON:0001379	41.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.38

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.