RTCA-AS1

Summary

RTCA-AS1 (RTCA antisense RNA 1, HGNC:50573) is a long non-coding RNA gene on chromosome 1p21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50573
Approved symbol	RTCA-AS1
Name	RTCA antisense RNA 1
Location	1p21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224616
Ensembl biotype	lncRNA
Entrez	100506007
RNAcentral	URS000075B7F8 — lncRNA, 780 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000421185, ENST00000650038, ENST00000653267, ENST00000665523, ENST00000666916, ENST00000670421

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421185 — 4 exons

Exon	Start	End
ENSE00001624870	100265815	100265917
ENSE00001703160	100266004	100266120
ENSE00001739375	100265068	100265247
ENSE00001769203	100264009	100264031

Expression profiles

Bgee: expression breadth ubiquitous, 215 present calls, max score 90.49.

FANTOM5 (CAGE): breadth broad, TPM avg 1.3581 / max 54.2742, expressed in 684 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
13515	1.3581	684

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	90.49	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.37	gold quality
colonic epithelium	UBERON:0000397	84.82	gold quality
monocyte	CL:0000576	82.82	gold quality
bone marrow cell	CL:0002092	82.50	gold quality
right uterine tube	UBERON:0001302	82.15	gold quality
leukocyte	CL:0000738	81.28	gold quality
mucosa of paranasal sinus	UBERON:0005030	79.46	gold quality
bronchial epithelial cell	CL:0002328	77.08	gold quality
bronchus	UBERON:0002185	75.44	gold quality
cortical plate	UBERON:0005343	74.17	gold quality
oviduct epithelium	UBERON:0004804	74.04	gold quality
adult mammalian kidney	UBERON:0000082	72.96	gold quality
cortex of kidney	UBERON:0001225	72.36	gold quality
fallopian tube	UBERON:0003889	72.25	gold quality
corpus callosum	UBERON:0002336	71.02	gold quality
right atrium auricular region	UBERON:0006631	70.96	gold quality
left ovary	UBERON:0002119	70.58	gold quality
islet of Langerhans	UBERON:0000006	70.53	gold quality
prefrontal cortex	UBERON:0000451	70.51	gold quality
kidney epithelium	UBERON:0004819	70.36	silver quality
right ovary	UBERON:0002118	70.33	gold quality
kidney	UBERON:0002113	70.32	gold quality
apex of heart	UBERON:0002098	70.14	gold quality
metanephros cortex	UBERON:0010533	69.82	gold quality
cardiac atrium	UBERON:0002081	69.72	gold quality
heart left ventricle	UBERON:0002084	69.50	gold quality
ventricular zone	UBERON:0003053	69.44	gold quality
calcaneal tendon	UBERON:0003701	69.38	gold quality
adenohypophysis	UBERON:0002196	69.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.