RUNX1-AS1

Summary

RUNX1-AS1 (RUNX1 antisense RNA 1, HGNC:56821) is a long non-coding RNA gene on chromosome 21q22.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56821
Approved symbol	RUNX1-AS1
Name	RUNX1 antisense RNA 1
Location	21q22.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286153
Ensembl biotype	lncRNA
Entrez	124905014
RNAcentral	URS00026A25F7 — lncRNA, 2204 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000651798, ENST00000701892

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000651798 — 2 exons

Exon	Start	End
ENSE00003846701	34883483	34884882
ENSE00003850137	34836286	34836946

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 92.08.

Top tissues by expression

114 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.08	gold quality
bone marrow cell	CL:0002092	79.54	gold quality
sural nerve	UBERON:0015488	75.05	gold quality
bone marrow	UBERON:0002371	73.01	gold quality
skeletal muscle tissue	UBERON:0001134	71.74	gold quality
colonic epithelium	UBERON:0000397	71.54	gold quality
adrenal tissue	UBERON:0018303	71.48	gold quality
left adrenal gland cortex	UBERON:0035825	67.37	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.50	gold quality
left adrenal gland	UBERON:0001234	66.29	gold quality
adrenal gland	UBERON:0002369	65.86	gold quality
tonsil	UBERON:0002372	65.28	gold quality
right adrenal gland cortex	UBERON:0035827	65.15	gold quality
stromal cell of endometrium	CL:0002255	64.67	gold quality
right adrenal gland	UBERON:0001233	64.20	gold quality
adipose tissue	UBERON:0001013	64.16	gold quality
liver	UBERON:0002107	63.71	gold quality
thoracic mammary gland	UBERON:0005200	63.56	gold quality
omental fat pad	UBERON:0010414	61.39	gold quality
calcaneal tendon	UBERON:0003701	60.84	gold quality
right lobe of liver	UBERON:0001114	59.16	gold quality
leukocyte	CL:0000738	58.29	gold quality
monocyte	CL:0000576	58.15	gold quality
granulocyte	CL:0000094	57.65	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.60	gold quality
blood	UBERON:0000178	56.11	gold quality
endometrium	UBERON:0001295	55.93	gold quality
minor salivary gland	UBERON:0001830	55.60	gold quality
gall bladder	UBERON:0002110	55.41	gold quality
saliva-secreting gland	UBERON:0001044	55.19	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.31
E-HCAD-30	no	88.34

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.