RUNX1-AS2

Summary

RUNX1-AS2 (RUNX1 antisense RNA 2, HGNC:58231) is a long non-coding RNA gene on chromosome 21q22.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58231
Approved symbol	RUNX1-AS2
Name	RUNX1 antisense RNA 2
Location	21q22.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234703
Ensembl biotype	lncRNA
Entrez	139355196
RNAcentral	URS0000410BD1 — lncRNA, 698 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000455028

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000455028 — 2 exons

Exon	Start	End
ENSE00001623290	35136638	35136849
ENSE00001764112	35138737	35139222

Expression profiles

Bgee: expression breadth broad, 28 present calls, max score 92.98.

Top tissues by expression

28 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.98	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.07	gold quality
ovary	UBERON:0000992	58.91	gold quality
prefrontal cortex	UBERON:0000451	55.58	gold quality
monocyte	CL:0000576	51.89	silver quality
islet of Langerhans	UBERON:0000006	48.75	gold quality
gall bladder	UBERON:0002110	48.75	gold quality
blood	UBERON:0000178	47.46	silver quality
gastrocnemius	UBERON:0001388	47.03	gold quality
heart left ventricle	UBERON:0002084	46.90	gold quality
esophagus	UBERON:0001043	46.11	gold quality
tonsil	UBERON:0002372	45.68	gold quality
ascending aorta	UBERON:0001496	44.13	gold quality
left coronary artery	UBERON:0001626	43.68	silver quality
omental fat pad	UBERON:0010414	42.18	gold quality
spleen	UBERON:0002106	41.86	silver quality
thoracic mammary gland	UBERON:0005200	41.30	silver quality
tibial artery	UBERON:0007610	40.79	silver quality
esophagus mucosa	UBERON:0002469	40.53	silver quality
muscle layer of sigmoid colon	UBERON:0035805	40.53	silver quality
minor salivary gland	UBERON:0001830	40.46	silver quality
skin of abdomen	UBERON:0001416	40.22	gold quality
skin of leg	UBERON:0001511	39.13	silver quality
fallopian tube	UBERON:0003889	38.67	silver quality
right lung	UBERON:0002167	38.64	silver quality
right atrium auricular region	UBERON:0006631	38.05	silver quality
body of stomach	UBERON:0001161	37.35	silver quality
left testis	UBERON:0004533	27.03	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.