RUNX3-AS1

Summary

RUNX3-AS1 (RUNX3 antisense RNA 1, HGNC:40513) is a long non-coding RNA gene on chromosome 1p36.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40513
Approved symbol	RUNX3-AS1
Name	RUNX3 antisense RNA 1
Location	1p36.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229162
Ensembl biotype	lncRNA
Entrez	105376878
RNAcentral	URS00026A282F — lncRNA, 4027 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000456316

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456316 — 3 exons

Exon	Start	End
ENSE00001700738	24962975	24963097
ENSE00001722301	24961345	24961846
ENSE00001805189	24962047	24962241

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 69.04.

Top tissues by expression

103 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	69.04	silver quality
bone marrow cell	CL:0002092	65.44	silver quality
tonsil	UBERON:0002372	64.97	gold quality
bone marrow	UBERON:0002371	58.89	gold quality
vermiform appendix	UBERON:0001154	58.61	gold quality
blood	UBERON:0000178	58.50	gold quality
lymph node	UBERON:0000029	58.25	gold quality
myometrium	UBERON:0001296	57.44	gold quality
granulocyte	CL:0000094	57.31	gold quality
cortex of kidney	UBERON:0001225	56.69	gold quality
endocervix	UBERON:0000458	56.12	gold quality
right lobe of liver	UBERON:0001114	55.63	gold quality
spleen	UBERON:0002106	55.61	gold quality
duodenum	UBERON:0002114	54.73	gold quality
small intestine	UBERON:0002108	54.62	gold quality
liver	UBERON:0002107	54.47	gold quality
leukocyte	CL:0000738	54.39	gold quality
small intestine Peyer’s patch	UBERON:0003454	54.26	gold quality
uterine cervix	UBERON:0000002	54.13	gold quality
gall bladder	UBERON:0002110	54.07	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.98	gold quality
rectum	UBERON:0001052	53.49	gold quality
monocyte	CL:0000576	53.38	gold quality
kidney	UBERON:0002113	52.72	gold quality
islet of Langerhans	UBERON:0000006	52.07	gold quality
urinary bladder	UBERON:0001255	51.71	gold quality
thoracic mammary gland	UBERON:0005200	51.30	gold quality
intestine	UBERON:0000160	50.34	gold quality
pancreas	UBERON:0001264	49.93	gold quality
saliva-secreting gland	UBERON:0001044	49.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.