RXYLT1-AS1

Summary

RXYLT1-AS1 (RXYLT1 antisense RNA 1, HGNC:48910) is a long non-coding RNA gene on chromosome 12q14.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48910
Approved symbol	RXYLT1-AS1
Name	RXYLT1 antisense RNA 1
Location	12q14.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255850
Ensembl biotype	lncRNA
Entrez	104169670
RNAcentral	URS000033973C — lncRNA, 563 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000546214, ENST00000649287, ENST00000741152, ENST00000741153, ENST00000741154

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546214 — 4 exons

Exon	Start	End
ENSE00002212598	63812207	63812307
ENSE00002279861	63808845	63808940
ENSE00004078034	63816201	63816338
ENSE00004078036	63821929	63822156

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 80.42.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.42	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.86	gold quality
colonic epithelium	UBERON:0000397	71.29	gold quality
cortical plate	UBERON:0005343	68.29	gold quality
calcaneal tendon	UBERON:0003701	60.33	gold quality
prefrontal cortex	UBERON:0000451	60.19	gold quality
urinary bladder	UBERON:0001255	58.68	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.10	gold quality
ganglionic eminence	UBERON:0004023	57.31	gold quality
skeletal muscle tissue	UBERON:0001134	56.72	gold quality
tibial artery	UBERON:0007610	56.10	gold quality
popliteal artery	UBERON:0002250	56.09	gold quality
lower esophagus	UBERON:0013473	55.85	gold quality
lower esophagus muscularis layer	UBERON:0035833	55.82	gold quality
smooth muscle tissue	UBERON:0001135	55.61	gold quality
descending thoracic aorta	UBERON:0002345	54.62	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	54.32	gold quality
vermiform appendix	UBERON:0001154	54.21	gold quality
frontal cortex	UBERON:0001870	53.91	gold quality
gall bladder	UBERON:0002110	53.43	gold quality
lymph node	UBERON:0000029	53.37	gold quality
placenta	UBERON:0001987	52.80	gold quality
left uterine tube	UBERON:0001303	52.56	gold quality
nucleus accumbens	UBERON:0001882	51.95	gold quality
myometrium	UBERON:0001296	51.93	gold quality
liver	UBERON:0002107	51.87	silver quality
esophagus	UBERON:0001043	51.62	gold quality
muscle layer of sigmoid colon	UBERON:0035805	51.46	gold quality
duodenum	UBERON:0002114	51.44	gold quality
primary visual cortex	UBERON:0002436	51.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.