RYR3-AS1

Summary

RYR3-AS1 (RYR3 antisense RNA 1, HGNC:58469) is a long non-coding RNA gene on chromosome 15q14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58469
Approved symbol	RYR3-AS1
Name	RYR3 antisense RNA 1
Location	15q14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259287
Ensembl biotype	lncRNA
Entrez	141858800

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000560268

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000560268 — 2 exons

Exon	Start	End
ENSE00002542763	33858602	33859094
ENSE00002567795	33864757	33864825

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 87.99.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.99	gold quality
right hemisphere of cerebellum	UBERON:0014890	76.39	gold quality
cerebellar hemisphere	UBERON:0002245	76.31	gold quality
cerebellar cortex	UBERON:0002129	76.22	gold quality
cerebellum	UBERON:0002037	76.00	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.39	gold quality
left uterine tube	UBERON:0001303	70.54	gold quality
body of uterus	UBERON:0009853	70.06	gold quality
cortical plate	UBERON:0005343	69.54	gold quality
colonic epithelium	UBERON:0000397	69.48	gold quality
right uterine tube	UBERON:0001302	69.07	gold quality
myometrium	UBERON:0001296	69.01	gold quality
smooth muscle tissue	UBERON:0001135	68.98	gold quality
granulocyte	CL:0000094	68.77	gold quality
right adrenal gland cortex	UBERON:0035827	68.71	gold quality
body of pancreas	UBERON:0001150	68.40	gold quality
lower esophagus muscularis layer	UBERON:0035833	68.10	gold quality
lower esophagus	UBERON:0013473	68.06	gold quality
fundus of stomach	UBERON:0001160	68.03	gold quality
gastrocnemius	UBERON:0001388	67.82	gold quality
left adrenal gland	UBERON:0001234	67.58	gold quality
left adrenal gland cortex	UBERON:0035825	67.54	gold quality
muscle of leg	UBERON:0001383	67.51	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	67.46	gold quality
apex of heart	UBERON:0002098	67.45	gold quality
ascending aorta	UBERON:0001496	67.42	gold quality
muscle layer of sigmoid colon	UBERON:0035805	67.27	gold quality
thoracic aorta	UBERON:0001515	67.26	gold quality
prostate gland	UBERON:0002367	67.22	gold quality
stromal cell of endometrium	CL:0002255	67.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.