RYR3-DT

Summary

RYR3-DT (RYR3 divergent transcript, HGNC:51417) is a long non-coding RNA gene on chromosome 15q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51417
Approved symbol	RYR3-DT
Name	RYR3 divergent transcript
Location	15q13.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_l2_00009005
Ensembl gene	ENSG00000259446
Ensembl biotype	lncRNA
Entrez	101928134
RNAcentral	URS000075D5A4 — lncRNA, 491 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000559457, ENST00000561458, ENST00000653439, ENST00000666561, ENST00000806977, ENST00000806978, ENST00000806979, ENST00000806980, ENST00000806981

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000559457 — 3 exons

Exon	Start	End
ENSE00002548094	33303657	33303938
ENSE00002567658	33306332	33306431
ENSE00004200544	33310578	33310696

Expression profiles

Bgee: expression breadth ubiquitous, 139 present calls, max score 80.34.

Top tissues by expression

222 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pancreatic ductal cell	CL:0002079	80.34	silver quality
tibialis anterior	UBERON:0001385	75.96	silver quality
epithelial cell of pancreas	CL:0000083	75.09	gold quality
sural nerve	UBERON:0015488	73.24	gold quality
colonic epithelium	UBERON:0000397	71.52	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.63	gold quality
kidney epithelium	UBERON:0004819	69.06	gold quality
amygdala	UBERON:0001876	67.70	gold quality
superficial temporal artery	UBERON:0001614	67.02	gold quality
descending thoracic aorta	UBERON:0002345	66.80	gold quality
buccal mucosa cell	CL:0002336	66.74	silver quality
nasal cavity epithelium	UBERON:0005384	66.47	gold quality
cardiac muscle of right atrium	UBERON:0003379	66.44	gold quality
substantia nigra	UBERON:0002038	66.16	gold quality
left ventricle myocardium	UBERON:0006566	66.16	gold quality
ectocervix	UBERON:0012249	65.58	gold quality
upper arm skin	UBERON:0004263	65.15	gold quality
quadriceps femoris	UBERON:0001377	64.99	gold quality
tibial artery	UBERON:0007610	64.85	gold quality
midbrain	UBERON:0001891	64.83	gold quality
body of uterus	UBERON:0009853	64.82	gold quality
popliteal artery	UBERON:0002250	64.80	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	64.20	gold quality
smooth muscle tissue	UBERON:0001135	64.18	gold quality
vastus lateralis	UBERON:0001379	63.94	gold quality
anterior cingulate cortex	UBERON:0009835	63.88	gold quality
aorta	UBERON:0000947	63.63	gold quality
putamen	UBERON:0001874	63.29	gold quality
right coronary artery	UBERON:0001625	63.26	gold quality
muscle layer of sigmoid colon	UBERON:0035805	63.22	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.