S1PR1-DT

Summary

S1PR1-DT (S1PR1 divergent transcript, HGNC:55842) is a long non-coding RNA gene on chromosome 1p21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55842
Approved symbol	S1PR1-DT
Name	S1PR1 divergent transcript
Location	1p21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	LISPR1
Ensembl gene	ENSG00000225938
Ensembl biotype	lncRNA
Entrez	101928370
RNAcentral	URS000075BD3C — lncRNA, 1222 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000432195, ENST00000686331, ENST00000820226, ENST00000820227, ENST00000820228

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432195 — 2 exons

Exon	Start	End
ENSE00004225967	101234129	101235881
ENSE00004225968	101236325	101236650

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 78.09.

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	78.09	gold quality
omental fat pad	UBERON:0010414	77.01	gold quality
peritoneum	UBERON:0002358	76.91	gold quality
adipose tissue of abdominal region	UBERON:0007808	75.87	gold quality
granulocyte	CL:0000094	75.50	gold quality
right lung	UBERON:0002167	75.09	gold quality
subcutaneous adipose tissue	UBERON:0002190	74.67	gold quality
right atrium auricular region	UBERON:0006631	73.59	gold quality
upper lobe of left lung	UBERON:0008952	72.78	gold quality
cardiac atrium	UBERON:0002081	72.74	gold quality
spleen	UBERON:0002106	72.71	gold quality
apex of heart	UBERON:0002098	72.53	gold quality
heart left ventricle	UBERON:0002084	71.71	gold quality
upper lobe of lung	UBERON:0008948	71.22	gold quality
lymph node	UBERON:0000029	71.16	gold quality
smooth muscle tissue	UBERON:0001135	71.13	gold quality
right coronary artery	UBERON:0001625	71.08	gold quality
adipose tissue	UBERON:0001013	70.98	gold quality
cardiac ventricle	UBERON:0002082	70.96	gold quality
heart	UBERON:0000948	70.68	gold quality
gall bladder	UBERON:0002110	70.58	gold quality
ganglionic eminence	UBERON:0004023	69.55	gold quality
vermiform appendix	UBERON:0001154	69.40	gold quality
amygdala	UBERON:0001876	68.67	gold quality
ventricular zone	UBERON:0003053	68.67	gold quality
bone marrow cell	CL:0002092	68.46	silver quality
mucosa of stomach	UBERON:0001199	68.34	gold quality
left coronary artery	UBERON:0001626	68.31	gold quality
nucleus accumbens	UBERON:0001882	68.11	gold quality
caudate nucleus	UBERON:0001873	67.41	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.64
E-HCAD-30	no	116.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.