SACK1A-AS2

Summary

SACK1A-AS2 (SACK1A antisense RNA 2, HGNC:56225) is a long non-coding RNA gene on chromosome 8q24.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56225
Approved symbol	SACK1A-AS2
Name	SACK1A antisense RNA 2
Location	8q24.13
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC068228.1
Ensembl gene	ENSG00000253258
Ensembl biotype	lncRNA
Entrez	125177378
RNAcentral	URS00028539D2 — lncRNA, 1493 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000522383

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000522383 — 2 exons

Exon	Start	End
ENSE00002104595	123181638	123182152
ENSE00002118267	123182527	123182788

Expression profiles

Bgee: expression breadth broad, 65 present calls, max score 96.87.

Top tissues by expression

65 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	96.87	gold quality
thoracic mammary gland	UBERON:0005200	96.57	gold quality
skeletal muscle tissue	UBERON:0001134	71.34	gold quality
colon	UBERON:0001155	66.28	gold quality
urinary bladder	UBERON:0001255	63.61	gold quality
lower esophagus mucosa	UBERON:0035834	63.08	gold quality
pancreas	UBERON:0001264	60.56	gold quality
left ovary	UBERON:0002119	60.25	gold quality
stomach	UBERON:0000945	58.08	gold quality
esophagus mucosa	UBERON:0002469	56.42	gold quality
esophagus	UBERON:0001043	56.26	gold quality
islet of Langerhans	UBERON:0000006	56.10	gold quality
myometrium	UBERON:0001296	55.45	gold quality
ectocervix	UBERON:0012249	54.88	gold quality
liver	UBERON:0002107	53.03	silver quality
multicellular organism	UBERON:0000468	51.43	gold quality
vagina	UBERON:0000996	51.43	gold quality
gall bladder	UBERON:0002110	51.42	gold quality
caudate nucleus	UBERON:0001873	50.66	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.85	gold quality
lower esophagus muscularis layer	UBERON:0035833	48.94	gold quality
blood	UBERON:0000178	48.77	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	48.43	gold quality
minor salivary gland	UBERON:0001830	48.21	gold quality
muscle of leg	UBERON:0001383	47.65	gold quality
right lobe of liver	UBERON:0001114	47.39	silver quality
gastrocnemius	UBERON:0001388	47.16	gold quality
tonsil	UBERON:0002372	47.09	gold quality
small intestine	UBERON:0002108	46.82	silver quality
putamen	UBERON:0001874	46.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.