SACK1C-AS1

Summary

SACK1C-AS1 (SACK1C antisense RNA 1, HGNC:16113) is a long non-coding RNA gene on chromosome 20q11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16113
Approved symbol	SACK1C-AS1
Name	SACK1C antisense RNA 1
Location	20q11.22
Locus type	RNA, long non-coding
Status	Approved
Aliases	dJ614O4.3
Ensembl gene	ENSG00000235214
Ensembl biotype	lncRNA
Entrez	140846
RNAcentral	URS000075BC43 — lncRNA, 368 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000429167, ENST00000765530, ENST00000765531, ENST00000765532, ENST00000765533, ENST00000765534, ENST00000765535, ENST00000765536, ENST00000765537

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429167 — 4 exons

Exon	Start	End
ENSE00001717891	35285470	35285756
ENSE00004123460	35284299	35284418
ENSE00004123468	35285162	35285315
ENSE00004123473	35284961	35285065

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 90.32.

Top tissues by expression

233 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.32	gold quality
sperm	CL:0000019	88.09	silver quality
right testis	UBERON:0004534	82.38	gold quality
left testis	UBERON:0004533	81.02	gold quality
testis	UBERON:0000473	77.70	gold quality
skin of leg	UBERON:0001511	68.82	gold quality
lower esophagus mucosa	UBERON:0035834	67.99	gold quality
skin of abdomen	UBERON:0001416	66.80	gold quality
zone of skin	UBERON:0000014	65.82	gold quality
buccal mucosa cell	CL:0002336	65.20	gold quality
right lobe of liver	UBERON:0001114	64.28	gold quality
ectocervix	UBERON:0012249	64.01	gold quality
cartilage tissue	UBERON:0002418	63.82	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	63.55	gold quality
endothelial cell	CL:0000115	63.07	gold quality
deltoid	UBERON:0001476	62.96	gold quality
mucosa of transverse colon	UBERON:0004991	62.77	gold quality
gall bladder	UBERON:0002110	62.30	gold quality
pons	UBERON:0000988	61.69	gold quality
islet of Langerhans	UBERON:0000006	60.93	gold quality
prefrontal cortex	UBERON:0000451	60.83	gold quality
saphenous vein	UBERON:0007318	60.66	gold quality
vena cava	UBERON:0004087	60.38	gold quality
cerebellar cortex	UBERON:0002129	60.31	gold quality
trabecular bone tissue	UBERON:0002483	60.30	gold quality
cerebellar hemisphere	UBERON:0002245	60.25	gold quality
esophagus mucosa	UBERON:0002469	60.25	gold quality
right hemisphere of cerebellum	UBERON:0014890	60.07	gold quality
pericardium	UBERON:0002407	59.73	gold quality
quadriceps femoris	UBERON:0001377	59.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• The oncogenic role of LncRNA FAM83C-AS1 in colorectal cancer development by epigenetically inhibits SEMA3F via stabilizing EZH2. (PMID:33109776)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.