SAMD12-AS1

Summary

SAMD12-AS1 (SAMD12 antisense RNA 1, HGNC:30937) is a long non-coding RNA gene on chromosome 8q24.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30937
Approved symbol	SAMD12-AS1
Name	SAMD12 antisense RNA 1
Location	8q24.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000281641
Ensembl biotype	lncRNA
Entrez	552860
RNAcentral	URS000075BAE3 — lncRNA, 701 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000625758, ENST00000629661, ENST00000658340, ENST00000659669, ENST00000664584, ENST00000818910

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000625758 — 8 exons

Exon	Start	End
ENSE00003761077	118725936	118726067
ENSE00003766372	118764269	118764384
ENSE00003767818	118620498	118621186
ENSE00003770326	118621535	118621655
ENSE00003771320	118724519	118724628
ENSE00003773818	118668450	118668601
ENSE00003868769	118904985	118906091
ENSE00003881512	118903659	118903779

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 81.84.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0459 / max 4.1100, expressed in 18 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
90361	0.0329	11
90362	0.0131	2

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.84	gold quality
colonic epithelium	UBERON:0000397	69.74	gold quality
islet of Langerhans	UBERON:0000006	60.10	gold quality
calcaneal tendon	UBERON:0003701	59.32	gold quality
stromal cell of endometrium	CL:0002255	57.88	gold quality
cortical plate	UBERON:0005343	56.60	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	54.99	gold quality
prefrontal cortex	UBERON:0000451	53.95	gold quality
pancreas	UBERON:0001264	53.86	gold quality
monocyte	CL:0000576	53.17	gold quality
gall bladder	UBERON:0002110	53.16	gold quality
liver	UBERON:0002107	53.03	silver quality
lymph node	UBERON:0000029	52.92	gold quality
urinary bladder	UBERON:0001255	52.26	gold quality
duodenum	UBERON:0002114	51.79	gold quality
bone marrow	UBERON:0002371	50.71	silver quality
blood	UBERON:0000178	50.46	gold quality
corpus callosum	UBERON:0002336	50.21	silver quality
rectum	UBERON:0001052	50.00	gold quality
cortex of kidney	UBERON:0001225	49.88	gold quality
frontal cortex	UBERON:0001870	49.83	gold quality
tonsil	UBERON:0002372	49.67	gold quality
kidney	UBERON:0002113	49.64	gold quality
adult mammalian kidney	UBERON:0000082	49.56	gold quality
endometrium	UBERON:0001295	49.39	silver quality
primary visual cortex	UBERON:0002436	49.11	silver quality
popliteal artery	UBERON:0002250	48.82	gold quality
tibial artery	UBERON:0007610	48.76	gold quality
superior frontal gyrus	UBERON:0002661	48.71	gold quality
esophagus mucosa	UBERON:0002469	48.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.07

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LncRNA SAMD12-AS1 Promotes the Progression of Gastric Cancer via DNMT1/p53 Axis. (PMID:33962804)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.