SAMD4A-AS1

Summary

SAMD4A-AS1 (SAMD4A antisense RNA 1, HGNC:54803) is a long non-coding RNA gene on chromosome 14q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54803
Approved symbol	SAMD4A-AS1
Name	SAMD4A antisense RNA 1
Location	14q22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc-GCH1-2:3
Ensembl gene	ENSG00000285774
Ensembl biotype	lncRNA
Entrez	729451
RNAcentral	URS00026A1F89 — lncRNA, 2042 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000648102, ENST00000655147, ENST00000674885, ENST00000676278, ENST00000691091, ENST00000810844

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000648102 — 3 exons

Exon	Start	End
ENSE00003831681	54687300	54687912
ENSE00003835828	54684753	54685001
ENSE00003837393	54685737	54685875

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 85.87.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
hindlimb stylopod muscle	UBERON:0004252	85.87	gold quality
monocyte	CL:0000576	84.14	gold quality
right testis	UBERON:0004534	83.70	gold quality
skeletal muscle tissue	UBERON:0001134	83.45	gold quality
left testis	UBERON:0004533	82.92	gold quality
leukocyte	CL:0000738	82.88	gold quality
testis	UBERON:0000473	82.47	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.34	gold quality
heart left ventricle	UBERON:0002084	78.34	gold quality
muscle of leg	UBERON:0001383	77.47	gold quality
gastrocnemius	UBERON:0001388	76.24	gold quality
apex of heart	UBERON:0002098	75.84	gold quality
muscle tissue	UBERON:0002385	75.37	gold quality
heart	UBERON:0000948	73.16	gold quality
right atrium auricular region	UBERON:0006631	72.43	gold quality
sural nerve	UBERON:0015488	71.36	gold quality
bone marrow cell	CL:0002092	68.75	silver quality
calcaneal tendon	UBERON:0003701	68.36	gold quality
colonic epithelium	UBERON:0000397	66.94	silver quality
granulocyte	CL:0000094	66.61	gold quality
blood	UBERON:0000178	66.47	gold quality
tonsil	UBERON:0002372	62.30	silver quality
corpus callosum	UBERON:0002336	59.03	gold quality
bone marrow	UBERON:0002371	58.73	gold quality
ascending aorta	UBERON:0001496	58.08	gold quality
urinary bladder	UBERON:0001255	58.02	gold quality
liver	UBERON:0002107	57.34	gold quality
thoracic aorta	UBERON:0001515	57.18	gold quality
stromal cell of endometrium	CL:0002255	56.49	gold quality
multicellular organism	UBERON:0000468	54.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.20

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.