SAP30-DT

Summary

SAP30-DT (SAP30 divergent transcript, HGNC:54424) is a long non-coding RNA gene on chromosome 4q34.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54424
Approved symbol	SAP30-DT
Name	SAP30 divergent transcript
Location	4q34.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000608794, MIRE
Ensembl gene	ENSG00000272870
Ensembl biotype	lncRNA
Entrez	105377540
RNAcentral	URS0000D59DDA — lncRNA, 1003 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000608794, ENST00000608892, ENST00000609153, ENST00000609900, ENST00000651702, ENST00000658397, ENST00000666010, ENST00000725023, ENST00000725024, ENST00000725025, ENST00000725026, ENST00000725027, ENST00000725028, ENST00000725029

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000608794 — 2 exons

Exon	Start	End
ENSE00003706339	173369434	173369815
ENSE00003707251	173363994	173364198

Expression profiles

Bgee: expression breadth ubiquitous, 169 present calls, max score 93.60.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.7444 / max 162.8225, expressed in 1050 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
54862	3.2933	984
54861	0.3421	156
54860	0.1090	20

Top tissues by expression

278 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	93.60	gold quality
tibial artery	UBERON:0007610	88.45	gold quality
popliteal artery	UBERON:0002250	88.44	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	87.29	gold quality
muscle layer of sigmoid colon	UBERON:0035805	87.03	gold quality
aorta	UBERON:0000947	86.85	gold quality
lower esophagus muscularis layer	UBERON:0035833	86.41	gold quality
lower esophagus	UBERON:0013473	86.37	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	86.36	gold quality
descending thoracic aorta	UBERON:0002345	86.15	gold quality
ventricular zone	UBERON:0003053	85.54	gold quality
ascending aorta	UBERON:0001496	85.42	gold quality
thoracic aorta	UBERON:0001515	85.37	gold quality
left coronary artery	UBERON:0001626	85.33	gold quality
mucosa of stomach	UBERON:0001199	85.25	gold quality
tibial nerve	UBERON:0001323	85.08	gold quality
cerebellar hemisphere	UBERON:0002245	83.45	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.44	gold quality
cerebellar cortex	UBERON:0002129	83.20	gold quality
right uterine tube	UBERON:0001302	83.05	gold quality
left ovary	UBERON:0002119	82.94	gold quality
coronary artery	UBERON:0001621	82.67	gold quality
spinal cord	UBERON:0002240	82.65	gold quality
ganglionic eminence	UBERON:0004023	82.53	gold quality
right coronary artery	UBERON:0001625	82.26	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.62	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	81.58	gold quality
body of uterus	UBERON:0009853	81.48	gold quality
right atrium auricular region	UBERON:0006631	81.38	gold quality
right ovary	UBERON:0002118	81.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.10

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• c-Myc-induced long noncoding RNA MIRE cooperates with hnRNPK to stabilize ELF2 mRNA and promotes clear cell renal cell carcinogenesis. (PMID:37248433)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.