SCARNA18B

Summary

SCARNA18B (small Cajal body-specific RNA 18B, HGNC:52236) is a small nucleolar RNA gene on chromosome 1q31.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 107397392 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52236
Approved symbol	SCARNA18B
Name	small Cajal body-specific RNA 18B
Location	1q31.2
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000238754
Ensembl biotype	snoRNA
Entrez	107397392
RNAcentral	URS000067D430 — ncRNA, 135 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000458806

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458806 — 1 exons

Exon	Start	End
ENSE00001807355	193057281	193057415

Expression profiles

Bgee: expression breadth broad, 72 present calls, max score 85.12.

Top tissues by expression

72 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adult mammalian kidney	UBERON:0000082	85.12	gold quality
kidney	UBERON:0002113	81.17	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	79.48	gold quality
monocyte	CL:0000576	78.84	gold quality
calcaneal tendon	UBERON:0003701	78.53	gold quality
stomach	UBERON:0000945	77.67	gold quality
corpus callosum	UBERON:0002336	77.19	gold quality
liver	UBERON:0002107	76.89	gold quality
blood	UBERON:0000178	75.16	gold quality
bone marrow	UBERON:0002371	74.48	gold quality
islet of Langerhans	UBERON:0000006	72.90	gold quality
endometrium	UBERON:0001295	71.83	gold quality
adrenal tissue	UBERON:0018303	70.86	gold quality
lung	UBERON:0002048	69.87	gold quality
pancreas	UBERON:0001264	69.72	gold quality
heart	UBERON:0000948	68.77	gold quality
substantia nigra	UBERON:0002038	67.74	gold quality
body of pancreas	UBERON:0001150	67.54	gold quality
left coronary artery	UBERON:0001626	67.35	gold quality
body of stomach	UBERON:0001161	67.14	gold quality
intestine	UBERON:0000160	67.06	gold quality
right coronary artery	UBERON:0001625	66.64	gold quality
heart left ventricle	UBERON:0002084	66.37	gold quality
omental fat pad	UBERON:0010414	66.30	gold quality
left uterine tube	UBERON:0001303	65.99	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.79	gold quality
minor salivary gland	UBERON:0001830	65.71	gold quality
fundus of stomach	UBERON:0001160	65.30	gold quality
esophagus mucosa	UBERON:0002469	65.02	gold quality
rectum	UBERON:0001052	64.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.60

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm25663	ENSMUSG00000088323
rattus_norvegicus	Scarna18b	ENSRNOG00000056434

Paralogs (7): (ENSG00000238410), (ENSG00000238575), (ENSG00000238832), SCARNA18 (ENSG00000238835), (ENSG00000239197), (ENSG00000252040), (ENSG00000252640)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.