SCARNA22

Summary

SCARNA22 (small Cajal body-specific RNA 22, HGNC:32580) is a small Cajal body RNA gene on chromosome 4p16.3.

Predicted to be involved in RNA processing. Predicted to be located in Cajal body and nucleolus.

Source: NCBI Gene 677770 — RefSeq curated summary.

At a glance

• Gene type: non-coding (scaRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32580
Approved symbol	SCARNA22
Name	small Cajal body-specific RNA 22
Location	4p16.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ACA11
Ensembl gene	ENSG00000249784
Ensembl biotype	scaRNA
Entrez	677770
RNAcentral	URS00003B6A48 — ncRNA, 125 nt, 7 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 scaRNA

ENST00000503991

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503991 — 1 exons

Exon	Start	End
ENSE00003540116	1974636	1974760

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 98.94.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1940 / max 12.1993, expressed in 94 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46582	0.1940	94

Top tissues by expression

87 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.94	gold quality
adrenal tissue	UBERON:0018303	95.98	gold quality
kidney	UBERON:0002113	91.42	gold quality
blood	UBERON:0000178	87.46	gold quality
stomach	UBERON:0000945	85.98	gold quality
liver	UBERON:0002107	84.02	gold quality
monocyte	CL:0000576	81.31	gold quality
lung	UBERON:0002048	80.15	gold quality
adult mammalian kidney	UBERON:0000082	79.82	gold quality
lymph node	UBERON:0000029	75.48	gold quality
skeletal muscle tissue	UBERON:0001134	74.01	gold quality
bone marrow	UBERON:0002371	73.76	gold quality
duodenum	UBERON:0002114	73.16	gold quality
islet of Langerhans	UBERON:0000006	72.49	gold quality
heart	UBERON:0000948	72.47	gold quality
intestine	UBERON:0000160	71.58	gold quality
vermiform appendix	UBERON:0001154	70.13	gold quality
muscle of leg	UBERON:0001383	69.36	gold quality
rectum	UBERON:0001052	67.82	gold quality
body of pancreas	UBERON:0001150	67.65	gold quality
multicellular organism	UBERON:0000468	66.67	gold quality
colon	UBERON:0001155	66.39	gold quality
gastrocnemius	UBERON:0001388	66.28	gold quality
prefrontal cortex	UBERON:0000451	65.01	gold quality
body of stomach	UBERON:0001161	64.51	gold quality
right lobe of liver	UBERON:0001114	64.33	gold quality
lower esophagus muscularis layer	UBERON:0035833	63.78	gold quality
left coronary artery	UBERON:0001626	63.64	gold quality
tibial artery	UBERON:0007610	63.54	gold quality
thoracic mammary gland	UBERON:0005200	63.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	17.66

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (1): SCARNA23 (ENSG00000251869)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.