SCARNA27

Summary

SCARNA27 (small Cajal body-specific RNA 27, HGNC:33614) is a gene on chromosome 6p24.3.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33614
Approved symbol	SCARNA27
Name	small Cajal body-specific RNA 27
Location	6p24.3
Locus type	RNA, small nucleolar
Status	Approved
Entrez	100124533
RNAcentral	URS0000759B0C — ncRNA, 126 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000041649 (6:8087392 A>G), RS1001862704 (6:8087846 T>C), RS1002914889 (6:8088283 C>T), RS1002948031 (6:8087966 C>T), RS1003540582 (6:8086606 T>C), RS1004369570 (6:8087889 T>C), RS1004402147 (6:8087733 C>G,T), RS1005049801 (6:8086282 G>A), RS1005378072 (6:8086727 A>G), RS1005407429 (6:8086441 C>G), RS1005577183 (6:8086513 T>C), RS1006953352 (6:8086040 G>A), RS1007351338 (6:8088498 G>C), RS1009141075 (6:8087406 T>C), RS1009981054 (6:8087065 C>T)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
hydroxyhydroquinone	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.