SCAT8

Summary

SCAT8 (S-phase cancer associated transcript 8, HGNC:40967) is a long non-coding RNA gene on chromosome 6q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40967
Approved symbol	SCAT8
Name	S-phase cancer associated transcript 8
Location	6q12
Locus type	RNA, long non-coding
Status	Approved
Aliases	EYS-AS1
Ensembl gene	ENSG00000236345
Ensembl biotype	lncRNA
Entrez	112935969
RNAcentral	URS0000390B3B — lncRNA, 1454 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000429530, ENST00000689151

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429530 — 2 exons

Exon	Start	End
ENSE00004230169	63821240	63822699
ENSE00004230170	63806767	63806886

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 79.08.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2253 / max 38.0198, expressed in 93 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
68413	0.1151	45
68412	0.1101	49

Top tissues by expression

114 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.08	silver quality
skeletal muscle tissue	UBERON:0001134	76.39	gold quality
monocyte	CL:0000576	73.72	gold quality
leukocyte	CL:0000738	73.62	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	70.84	gold quality
blood	UBERON:0000178	70.22	gold quality
islet of Langerhans	UBERON:0000006	66.46	gold quality
bone marrow cell	CL:0002092	66.10	silver quality
granulocyte	CL:0000094	66.08	gold quality
colonic epithelium	UBERON:0000397	65.74	silver quality
gastrocnemius	UBERON:0001388	64.59	gold quality
muscle of leg	UBERON:0001383	63.97	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.11	gold quality
cortical plate	UBERON:0005343	58.40	silver quality
pancreas	UBERON:0001264	56.98	gold quality
endometrium	UBERON:0001295	56.33	gold quality
bone marrow	UBERON:0002371	56.13	gold quality
liver	UBERON:0002107	55.25	gold quality
vagina	UBERON:0000996	52.51	gold quality
placenta	UBERON:0001987	52.23	gold quality
cortex of kidney	UBERON:0001225	51.56	gold quality
spleen	UBERON:0002106	51.44	gold quality
multicellular organism	UBERON:0000468	51.41	gold quality
right lobe of liver	UBERON:0001114	51.10	gold quality
smooth muscle tissue	UBERON:0001135	50.87	gold quality
gall bladder	UBERON:0002110	50.77	gold quality
duodenum	UBERON:0002114	50.32	gold quality
lymph node	UBERON:0000029	50.15	silver quality
body of pancreas	UBERON:0001150	50.14	gold quality
ectocervix	UBERON:0012249	49.55	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.