SCOC-AS1

Summary

SCOC-AS1 (SCOC antisense RNA 1, HGNC:50601) is a long non-coding RNA gene on chromosome 4q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50601
Approved symbol	SCOC-AS1
Name	SCOC antisense RNA 1
Location	4q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000196951
Ensembl biotype	lncRNA
Entrez	100129858
RNAcentral	URS000075D09A — lncRNA, 2017 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000512692, ENST00000608178, ENST00000609616, ENST00000658255, ENST00000664103, ENST00000693274, ENST00000747061, ENST00000747062, ENST00000747063, ENST00000747064, ENST00000747065, ENST00000747066, ENST00000747067, ENST00000747068, ENST00000747069, ENST00000747070, ENST00000747071, ENST00000811644

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000512692 — 5 exons

Exon	Start	End
ENSE00002021443	140283724	140285268
ENSE00002022657	140291390	140291529
ENSE00002023228	140369310	140369350
ENSE00002050436	140293261	140293423
ENSE00003877459	140373263	140373384

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 82.13.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.2878 / max 94.3440, expressed in 1007 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
54119	2.2878	1007

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	82.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.62	gold quality
left testis	UBERON:0004533	81.25	gold quality
right atrium auricular region	UBERON:0006631	80.39	gold quality
cardiac atrium	UBERON:0002081	79.49	gold quality
testis	UBERON:0000473	78.87	gold quality
apex of heart	UBERON:0002098	78.62	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	78.60	gold quality
heart left ventricle	UBERON:0002084	76.00	gold quality
spinal cord	UBERON:0002240	75.20	gold quality
islet of Langerhans	UBERON:0000006	74.81	gold quality
cardiac ventricle	UBERON:0002082	74.80	gold quality
heart	UBERON:0000948	74.06	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.87	gold quality
granulocyte	CL:0000094	73.53	gold quality
left adrenal gland cortex	UBERON:0035825	72.84	gold quality
right adrenal gland	UBERON:0001233	72.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.75	gold quality
left adrenal gland	UBERON:0001234	72.50	gold quality
bone marrow cell	CL:0002092	72.06	silver quality
stromal cell of endometrium	CL:0002255	71.55	gold quality
hypothalamus	UBERON:0001898	71.50	gold quality
right adrenal gland cortex	UBERON:0035827	71.49	gold quality
adenohypophysis	UBERON:0002196	70.85	gold quality
putamen	UBERON:0001874	70.54	gold quality
adrenal gland	UBERON:0002369	70.42	gold quality
nucleus accumbens	UBERON:0001882	70.41	gold quality
adrenal cortex	UBERON:0001235	70.31	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.23	gold quality
colonic epithelium	UBERON:0000397	70.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.25

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Association of Circulating Biomarkers of lnc-IGSF3-1:1, SCOC-AS1, and SLC8A1-AS1 with Salt Sensitivity of Blood Pressure in Chinese Population. (PMID:34855149)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.